ArticleJournal of the American Heart Association2016
Smoking, Smoking Cessation, and Measures of Subclinical Atherosclerosis in Multiple Vascular Beds in Japanese Men.
Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 54 citations in OpenAlex.
- Let's be CLEAR: Cath Lab Evaluation of Atherosclerotic Risk is a disease modifying opportunity.The British journal of cardiology · 2026Article
- The Effects of Nicotine on Re-endothelialization, Inflammation, and Neoatherosclerosis After Drug-Eluting Stent Implantation in a Porcine Model.Korean circulation journal · 2025Article
- An explainable CT-based machine learning model integrating carotid plaque and perivascular adipose tissue for predicting symptomatic plaques.Frontiers in neurology · 2025Article
- Association of Anthropometric and CT-Based Obesity Indices with Subclinical Atherosclerosis.Journal of atherosclerosis and thrombosis · 2024Article
- Article
- MRI-Measured Pancreatic Fat Correlates with Increased Arterial Stiffness in Patients Who are Overweight and Obese.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Smoking and secondhand smoke exposure and carotid intima-media thickness: Baseline data from the Aidai Cohort Study in Japan.Tobacco induced diseases · 2024Article
- The associations of cardiovascular and lifestyle factors with mortality from chronic kidney disease as the underlying cause: the JACC study.Epidemiology and health · 2024Article
- Association between smoking status and subclinical coronary atherosclerosis in asymptomatic Korean individuals.Epidemiology and health · 2024Article
- Coronary Artery Calcium in Assessment of Atherosclerotic Cardiovascular Disease Risk and its Role in Primary Prevention.Journal of atherosclerosis and thrombosis · 2023Review
- Fully automated calcium scoring predicts all-cause mortality at 12 years in the MILD lung cancer screening trial.PloS one · 2023Article
- Biomarkers of Exposure and Potential Harm in Exclusive Users of Nicotine Pouches and Current, Former, and Never Smokers: Protocol for a Cross-sectional Clinical Study.JMIR research protocols · 2022Article
- Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.Cardiovascular research · 2022Article
- Nomogram and Carotid Risk Score for Predicting Moderate or High Carotid Atherosclerosis among Asymptomatic Elderly Recycling Volunteers.Diagnostics (Basel, Switzerland) · 2022Article
- Association between baseline smoking status and clinical outcomes following myocardial infarction.Frontiers in cardiovascular medicine · 2022Article
- Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021Review
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- Article
- Effect of cigarette smoking on carotid artery atherosclerosis: a community-based cohort study.Heart and vessels · 2020Article
- Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA).Journal of epidemiology · 2019Article
Corrections and comments
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Authors and funding
19 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSmoking is an overwhelming, but preventable, risk factor for cardiovascular diseases (CVD), although smoking prevalence remains high in developed and developing countries in East Asia. METHODS AND
resultsIn a population-based sample of 1019 Japanese men aged 40 to 79 years, without CVD, we examined cross-sectional associations of smoking status, cumulative pack-years, daily consumption, and time since cessation, with subclinical atherosclerosis at 4 anatomically distinct vascular beds, including coronary artery calcification, carotid intima-media thickness (CIMT) and plaque, aortic artery calcification (AoAC), and ankle-brachial index. Current, former, and never smoking were present in 32.3%, 50.0%, and 17.7%, respectively. Compared to never smokers, current smokers had significantly higher risks of subclinical atherosclerosis in all 4 circulations (eg, odds ratios for coronary artery calcification >0, 1.79 [95% CIs, 1.16-2.79]; CIMT >1.0 mm, 1.88 [1.02-3.47]; AoAC >0, 4.29 [2.30-7.97]; and ankle-brachial index <1.1, 1.78 [1.16-2.74]) and former smokers did in carotid and aortic circulations (CIMT >1.0 mm, 1.94 [1.13-3.34]; and AoAC >0, 2.55 [1.45-4.49]). Dose-response relationships of pack-years and daily consumption, particularly with CIMT, carotid plaque, AoAC, and ankle-brachial index, were observed among both current and former smokers, and even a small amount of pack-years or daily consumption among current smokers was associated with coronary artery calcification and AoAC, whereas time since cessation among former smokers was linearly associated with lower burdens of all atherosclerotic indices.
conclusionsCigarette smoking was strongly associated with subclinical atherosclerosis in multiple vascular beds in Japanese men, and these associations attenuated with time since cessation.
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