ReviewMethods in enzymology2016
High-Resolution Macromolecular Structure Determination by MicroED, a cryo-EM Method.
Review in Methods in enzymology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- An integrated workflow for the structure elucidation of nanocrystalline powders.Communications chemistry · 2026Article
- Studying Membrane Protein Structures by MicroED.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER.Acta crystallographica. Section D, Structural biology · 2020Article
- Molecular engineering strategies for visualizing low-affinity protein complexes.Experimental biology and medicine (Maywood, N.J.) · 2019Article
- Structure-based inhibitors of tau aggregation.Nature chemistry · 2018Article
- Taking the measure of MicroED.Current opinion in structural biology · 2017Review
- Protein structure determination by electron diffraction using a single three-dimensional nanocrystal.Acta crystallographica. Section D, Structural biology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Microelectron diffraction (MicroED) is a new cryo-electron microscopy (cryo-EM) method capable of determining macromolecular structures at atomic resolution from vanishingly small 3D crystals. MicroED promises to solve atomic resolution structures from even the tiniest of crystals, less than a few hundred nanometers thick. MicroED complements frontier advances in crystallography and represents part of the rebirth of cryo-EM that is making macromolecular structure determination more accessible for all. Here we review the concept and practice of MicroED, for both the electron microscopist and crystallographer. Where other reviews have addressed specific details of the technique (Hattne et al., 2015; Shi et al., 2016; Shi, Nannenga, Iadanza, & Gonen, 2013), we aim to provide context and highlight important features that should be considered when performing a MicroED experiment.
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Registered trials
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