ArticleAntimicrobial agents and chemotherapy2016
Plasmid with Colistin Resistance Gene mcr-1 in Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains Isolated from Pig Slurry in Estonia.
Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Occurrence and Biological Cost ofAntibiotics (Basel, Switzerland) · 2022Article
- An Update of Mobile Colistin Resistance in Non-Fermentative Gram-Negative Bacilli.Frontiers in cellular and infection microbiology · 2022Review
- The Use of Colistin in Food-Producing Animals in Estonia-Vaccination as an Effective Alternative to Consumption of Critically Important Antimicrobials in Pigs.Antibiotics (Basel, Switzerland) · 2021Article
- Plasmid MediatedFrontiers in microbiology · 2021Article
- Antibiotics and Antibiotic Resistance Genes in Animal Manure - Consequences of Its Application in Agriculture.Frontiers in microbiology · 2021Review
- Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events.Veterinary sciences · 2020Review
- Emergence ofmSystems · 2020Article
- Occurrence and Characteristics of Mobile Colistin Resistance (International journal of environmental research and public health · 2020Review
- Antimicrobial Resistance and Food Animals: Influence of Livestock Environment on the Emergence and Dissemination of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2020Review
- Article
- Sequencing-based methods and resources to study antimicrobial resistance.Nature reviews. Genetics · 2019Review
- Conjugal Transfer, Whole-Genome Sequencing, and Plasmid Analysis of FourAntimicrobial agents and chemotherapy · 2019Article
- The rise and spread ofCritical reviews in microbiology · 2019Review
- Antimicrobial resistance of Escherichia coli and Enterococcus spp. isolated from Estonian cattle and swine from 2010 to 2015.Acta veterinaria Scandinavica · 2019Article
- Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong.BMC infectious diseases · 2018Article
- Article
- IncX2 and IncX1-X2 Hybrid Plasmids Coexisting in a FosA6-Producing Escherichia coli Strain.Antimicrobial agents and chemotherapy · 2017Article
- Next-generation approaches to understand and combat the antibiotic resistome.Nature reviews. Microbiology · 2017Review
- Various Sequence Types of Escherichia coli Isolates CoharboringAntimicrobial agents and chemotherapy · 2017Article
- Occurrence of theFrontiers in microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A plasmid carrying the colistin resistance gene mcr-1 was isolated from a pig slurry sample in Estonia. The gene was present on a 33,311-bp plasmid of the IncX4 group. mcr-1 is the only antibiotic resistance gene on the plasmid, with the other genes mainly coding for proteins involved in conjugative DNA transfer (taxA, taxB, taxC, trbM, and the pilX operon). The plasmid pESTMCR was present in three phylogenetically very different Escherichia coli strains, suggesting that it has high potential for horizontal transfer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.