Evidence map›Paper›PMID 27572335›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2017

2016 Updated MASCC/ESMO Consensus Recommendations: Controlling nausea and vomiting with chemotherapy of low or minimal emetic potential.

Ian Olver, Christina H Ruhlmann, Franziska Jahn, Lee Schwartzberg, Bernardo Rapoport, Cynthia N Rittenberg, Rebecca Clark-Snow

Abstract readSystematic ReviewConsensus Statement
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. 2023 updated MASCC/ESMO consensus recommendations: controlling nausea and vomiting with chemotherapy of low or minimal emetic potential.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  3. Review
  4. The core symptom in multiple myeloma patients undergoing chemotherapy: a network analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. A prospective, observational, multicenter study on risk factors and prophylaxis for low emetic risk chemotherapy-induced nausea and vomiting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  9. Review
  10. SEOM Clinical Guideline update for the prevention of chemotherapy-induced nausea and vomiting (2016).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2016
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Ian OlverSansom Institute for Health Research, University of South Australia, P5-06e Playford Building, City East Campus, GPO Box 2471, Adelaide, SA, 5001, Australia. ian.olver@unisa.edu.au.
Christina H RuhlmannDepartment of Oncology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
Franziska JahnDepartment of Hematology and Oncology, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle, Germany.
Lee SchwartzbergWest Cancer Center, University of Tennessee Health Science Center, Memphis, TN, USA.
Bernardo RapoportThe Medical Oncology Centre of Rosebank, 129 Oxford Road, Saxonwold, Johannesburg, 2196, South Africa.
Cynthia N RittenbergRittenberg Oncology Consulting, 500 Rue St. Ann, Suite 223, Metairie, LA, 70005, USA.
Rebecca Clark-SnowThe University of Kansas Cancer Center, 2330 Shawnee Mission Parkway, Westwood, KS, 66205, USA.
Martin Luther University Halle-Wittenberg · DEOdense University Hospital · DKThe Medical Oncology Centre of Rosebank · ZAThe University of Kansas Cancer Center · USUniversity of South Australia · AUUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this review is to update the MASCC (Multinational Association of Supportive Care in Cancer) guidelines for controlling nausea and vomiting with chemotherapy of low or minimal emetic potential.

methodsThe antiemetic study group of MASCC met in Copenhagen in 2015 to review the MASCC antiemetic guidelines. A subgroup performed a systematic literature review on antiemetics for low emetogenic chemotherapy (LEC) and chemotherapy of minimal emetic potential and the chair presented the update recommendation to the whole group for discussion. They then voted with an aim of achieving 67 % or greater consensus.

resultsFor patients receiving low emetogenic chemotherapy, a single antiemetic such as dexamethasone, a 5HT3 receptor antagonist, or a dopamine receptor antagonist may be considered for prophylaxis of acute emesis. For patients receiving chemotherapy of minimal emetogenicity, no antiemetic should be routinely administered. If patients vomit, they should be treated as for chemotherapy of low emetic potential. No antiemetic should be administered for prevention of delayed nausea and vomiting induced by low or minimally emetogenic chemotherapy.

conclusionsMore research is needed to determine the incidence of emesis, particularly delayed emesis, in the LEC group. Prospective studies are required to evaluate antiemetic strategies. The risk of emesis within LEC may be more accurately determined by adding the patient risk factors for emesis to those of the chemotherapy drugs. Improved strategies for promoting adherence to guidelines are required.

Indexed as

AntiemeticsAntineoplastic AgentsEmeticsHumansNauseaPractice Guidelines as TopicProspective StudiesVomitingAntiemeticsAntineoplastic AgentsEmeticsAntiemeticLow emetogenic chemotherapy (LEC)Minimal emetogenic chemotherapyMinimal emetogenicityNauseaVomiting

Identifiers

PMID27572335
OpenAlexW2509814394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.