ArticleeLife2016
Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- HJ Muller and the Relationship Between Sex Chromosome Degeneration and the Evolution of Dosage Compensation.Genome biology and evolution · 2025Review
- Repeated Evolution of Transcript Dosage Compensation of Independently Formed Nematode Neo-X Chromosomes.Genome biology and evolution · 2025Article
- Analysis of developmental gene expression using smFISH andbioRxiv : the preprint server for biology · 2024Article
- Genome-Wide Effects on Gene Expression Between Parental and Filial Generations of Trisomy 11 and 12 of Rice.Rice (New York, N.Y.) · 2023Article
- Combinatorial clustering of distinct DNA motifs directs synergistic binding ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Masculinizer-induced dosage compensation is achieved by transcriptional downregulation of both copies of Z-linked genes in the silkworm,Biology letters · 2022Article
- Modular safe-harbor transgene insertion for targeted single-copy and extrachromosomal array integration in Caenorhabditis elegans.G3 (Bethesda, Md.) · 2022Article
- Evolution of sexual systems, sex chromosomes and sex-linked gene transcription in flatworms and roundworms.Nature communications · 2022Article
- The X chromosome in C. elegans sex determination and dosage compensation.Current opinion in genetics & development · 2022Review
- Dosage compensation inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Review
- Do male and female heterogamety really differ in expression regulation? Lack of global dosage balance in pygopodid geckos.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Variable dosage compensation is associated with female consequences of an X-linked, male-beneficial mutation.Proceedings. Biological sciences · 2021Article
- Dose-dependent action of the RNA binding protein FOX-1 to relay X-chromosome number and determineeLife · 2020Article
- X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.Developmental cell · 2019Article
- Diverse Genome Topologies Characterize Dosage Compensation across Species.Trends in genetics : TIG · 2019Review
- Article
- Sex and death: from cell fate specification to dynamic control of X-chromosome structure and gene expression.Molecular biology of the cell · 2018Article
- Caenorhabditis elegans Dosage Compensation: Insights into Condensin-Mediated Gene Regulation.Trends in genetics : TIG · 2018Review
- Evolution of Sex Chromosome Dosage Compensation in Animals: A Beautiful Theory, Undermined by Facts and Bedeviled by Details.Genome biology and evolution · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Changes in chromosome number impair fitness by disrupting the balance of gene expression. Here we analyze mechanisms to compensate for changes in gene dose that accompanied the evolution of sex chromosomes from autosomes. Using single-copy transgenes integrated throughout the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.