ArticleeLife2016
Proton currents constrain structural models of voltage sensor activation.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- HInternational journal of molecular sciences · 2025Review
- Voltage sensors.Molecular pharmacology · 2025Review
- Interior pH-sensing residue of human voltage-gated proton channel HBiophysical journal · 2024Article
- Review
- Unexpected expansion of the voltage-gated proton channel family.The FEBS journal · 2023Article
- Article
- A novel Hv1 inhibitor reveals a new mechanism of inhibition of a voltage-sensing domain.The Journal of general physiology · 2021Article
- Discovery and characterization of HeLife · 2021Article
- Voltage-gated proton channels from fungi highlight role of peripheral regions in channel activation.Communications biology · 2021Article
- Voltage and pH difference across the membrane control the S4 voltage-sensor motion of the Hv1 proton channel.Scientific reports · 2020Article
- Zn2+ to probe voltage-gated proton (Hv1) channels.The Journal of general physiology · 2020Article
- Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel.The Journal of general physiology · 2020Article
- Insights on small molecule binding to the Hv1 proton channel from free energy calculations with molecular dynamics simulations.Scientific reports · 2020Article
- Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2019Review
- Gating charge displacement in a monomeric voltage-gated proton (HProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Gating Currents in the Hv1 Proton Channel.Biophysical journal · 2018Article
- Charge of the Proton Channel.Biophysical journal · 2018Article
- The acid test for pH-dependent gating in cloned HThe Journal of general physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The Hv1 proton channel is evidently unique among voltage sensor domain proteins in mediating an intrinsic 'aqueous' H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.