ArticleNature microbiology2016
Genomic inference of the metabolism of cosmopolitan subsurface Archaea, Hadesarchaea.
Article in Nature microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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76 citing papers in PubMed, 150 citations in OpenAlex.
- Exploring archaeal resources for biomass-derived pentose utilization: pathways, extremozymes, and bioprocessing applications.World journal of microbiology & biotechnology · 2026Review
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- Long vs. short read sequencing for microbial ecology of sedimentary environments: a case study from Lake Arnon, Switzerland.FEMS microbiology letters · 2026Article
- A genomic view of Earth's biomes.Nature reviews. Genetics · 2026Review
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- Wide Diversity and Complex Evolution of M42 Aminopeptidases With Contrasted Functional Properties in Archaea.Molecular biology and evolution · 2025Article
- The Deep Subsurface Biosphere and its Substrates Along a One-Million-Year Ferruginous Lake Archive.Microbial ecology · 2025Article
- Fungi promote cross-domain interactions even in deep anoxic mangrove sediments.Environmental microbiome · 2025Article
- Microbial ecology of serpentinite-hosted ecosystems.The ISME journal · 2025Review
- Microbial diversity and biogeochemical interactions in the seismically active and COEnvironmental microbiome · 2024Article
- Nature should be the model for microbial sciences.Journal of bacteriology · 2024Review
- Asgard archaea modulate potential methanogenesis substrates in wetland soil.Nature communications · 2024Article
- Species-resolved, single-cell respiration rates reveal dominance of sulfate reduction in a deep continental subsurface ecosystem.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Anaerobic hexadecane degradation by a thermophilic Hadarchaeon from Guaymas Basin.The ISME journal · 2024Article
- Metabolic features that select for Bathyarchaeia in modern ferruginous lacustrine subsurface sediments.ISME communications · 2024Article
- Metagenomic profiles of archaea and bacteria within thermal and geochemical gradients of the Guaymas Basin deep subsurface.Nature communications · 2023Article
- Archaeal and Extremophilic Bacteria from Different Archaeological Excavation Sites.International journal of molecular sciences · 2023Article
- Metabolic versatility ofFrontiers in microbiology · 2023Article
- Methanogen activity and microbial diversity in Gulf of Cádiz mud volcano sediments.Frontiers in microbiology · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The subsurface biosphere is largely unexplored and contains a broad diversity of uncultured microbes(1). Despite being one of the few prokaryotic lineages that is cosmopolitan in both the terrestrial and marine subsurface(2-4), the physiological and ecological roles of SAGMEG (South-African Gold Mine Miscellaneous Euryarchaeal Group) Archaea are unknown. Here, we report the metabolic capabilities of this enigmatic group as inferred from genomic reconstructions. Four high-quality (63-90% complete) genomes were obtained from White Oak River estuary and Yellowstone National Park hot spring sediment metagenomes. Phylogenomic analyses place SAGMEG Archaea as a deeply rooting sister clade of the Thermococci, leading us to propose the name Hadesarchaea for this new Archaeal class. With an estimated genome size of around 1.5 Mbp, the genomes of Hadesarchaea are distinctly streamlined, yet metabolically versatile. They share several physiological mechanisms with strict anaerobic Euryarchaeota. Several metabolic characteristics make them successful in the subsurface, including genes involved in CO and H2 oxidation (or H2 production), with potential coupling to nitrite reduction to ammonia (DNRA). This first glimpse into the metabolic capabilities of these cosmopolitan Archaea suggests they are mediating key geochemical processes and are specialized for survival in the subsurface biosphere.
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