Evidence map›Paper›PMID 27571904›Full record

ArticleThe Journal of infectious diseases2016

Viral Genome Sequencing Proves Nosocomial Transmission of Fatal Varicella.

Daniel P Depledge, Julianne Brown, Jasna Macanovic, Gill Underhill, Judith Breuer

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Alphaherpesvirus Genomics: Past, Present and Future.Current issues in molecular biology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Daniel P DepledgeDivision of Infection and Immunity, University College London.
Julianne BrownGreat Ormond Street Hospital VZV Reference Laboratory, Great Ormond Street Hospital, London.
Jasna MacanovicWessex Renal and Transplant Services.
Gill UnderhillDepartments of Clinical Microbiology, Pathology Centre, Queen Alexandra Hospital, Cosham, Portsmouth, United Kingdom.
Judith BreuerDivision of Infection and Immunity, University College London.
Institute of Infection and Immunity · CAQueen Alexandra Hospital · GBUniversity College London · GB

Funding

Medical Research Council G0700814MRF_ C0485
6 · The paper itself

Abstract

We report the first use of whole viral genome sequencing to identify nosocomial transmission of varicella-zoster virus with fatal outcome. The index case patient, nursed in source isolation, developed disseminated zoster with rash present for 1 day before being transferred to the intensive care unit (ICU). Two patients who had received renal transplants while inpatients in an adjacent ward developed chickenpox and 1 died; neither patient had direct contact with the index patient.

Indexed as

AgedChickenpoxCross InfectionFemaleGenome, ViralHerpesvirus 3, HumanHerpes ZosterHumansIntensive Care UnitsKidney TransplantationMaleMiddle Agedfatal varicellanosocomial transmissionwhole genome sequencing

Identifiers

PMID27571904
PMCPMC5079377
OpenAlexW2513984945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.