ArticleNature microbiology2016
An assessment of US microbiome research.
Article in Nature microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Financing and Reimbursement Models for Personalised Medicine: A Systematic Review to Identify Current Models and Future Options.Applied health economics and health policy · 2022Pooled it
- Influence of Maternal Prepregnancy Obesity and Excessive Gestational Weight Gain on Maternal and Child Gastrointestinal Microbiome Composition: A Systematic Review.Biological research for nursing · 2020Pooled it
- Microbiome Science Certificate Program for workforce development and multi-omics expertise.Journal of microbiology & biology education · 2026Article
- STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies.Nature microbiology · 2025Review
- Strengthening Integrative Microbiome Research Through Regional Leadership.International journal of environmental research and public health · 2025Article
- Microbiome data management in action workshop: Atlanta, GA, USA, June 12-13, 2024.Environmental microbiome · 2025Article
- Quantifying the impact of workshops promoting microbiome data standards and data stewardship.Scientific reports · 2025Article
- What is eDNA method standardisation and why do we need it?Metabarcoding and metagenomics · 2025Article
- Structure of anellovirus-like particles reveal a mechanism for immune evasion.Nature communications · 2024Article
- The Role of Gut Microbiota in Different Types of Physical Activity and Their Intensity: Systematic Review and Meta-Analysis.Sports (Basel, Switzerland) · 2024Review
- High-throughput DNA extraction strategy for fecal microbiome studies.Microbiology spectrum · 2024Article
- The microbiota-gut-brain-immune interface in the pathogenesis of neuroinflammatory diseases: a narrative review of the emerging literature.Frontiers in immunology · 2024Review
- Host influence on the eukaryotic virome of sympatric mosquitoes and abundance of diverse viruses with a broad host range.PloS one · 2024Article
- Optimization of a DNA extraction protocol for improving bacterial and fungal classification based on Nanopore sequencing.Access microbiology · 2024Article
- [Impact of preservatives in topicals on the cutaneous microbiota].Dermatologie (Heidelberg, Germany) · 2023Article
- Insights into the Methodological, Biotic and Abiotic Factors Influencing the Characterization of Xylem-Inhabiting Microbial Communities of Olive Trees.Plants (Basel, Switzerland) · 2023Review
- Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquitoVirus evolution · 2023Article
- Editing of a Specific Strain of Escherichia coli in the Mouse Gut Using Native Phages.Microbiology spectrum · 2022Article
- The Pre-Analytical CEN/TS Standard for Microbiome Diagnostics-How Can Research and Development Benefit?Nutrients · 2022Article
- Network structure of resource use and niche overlap within the endophytic microbiome.The ISME journal · 2022Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genome-enabled technologies have supported a dramatic increase in our ability to study microbial communities in environments and hosts. Taking stock of previously funded microbiome research can help to identify common themes, under-represented areas and research priorities to consider moving forward. To assess the status of US microbiome research, a team of government scientists conducted an analysis of federally funded microbiome research. Microbiomes were defined as host-, ecosystem- or habitat-associated communities of microorganisms, and microbiome research was defined as those studies that emphasize community-level analyses using 'omics technologies. Single pathogen, single strain and culture-based studies were not included, except symbiosis studies that served as models for more complex communities. Fourteen governmental organizations participated in the data call. The analysis examined three broad research themes, eight environments and eight microbial categories. Human microbiome research was larger than any other environment studied, and the basic biology research theme accounted for half of the total research activities. Computational biology and bioinformatics, reference databases and biorepositories, standardized protocols and high-throughput tools were commonly identified needs. Longitudinal and functional studies and interdisciplinary research were also identified as needs. This study has implications for the funding of future microbiome research, not only in the United States but beyond.
Indexed as
Identifiers
27571759What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.