ArticleNature methods2016
MetaMass, a tool for meta-analysis of subcellular proteomics data.
Article in Nature methods, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessing sub-cellular resolution in spatial proteomics experiments.Current opinion in chemical biology · 2019Pooled it
- C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels.Nature methods · 2026Article
- Altered Relaxation and Mitochondria-Endoplasmic Reticulum Contacts Precede Major (Mal)Adaptations in Aging Skeletal Muscle and Are Prevented by Exercise.Aging cell · 2025Article
- Recent Advancements in Subcellular Proteomics: Growing Impact of Organellar Protein Niches on the Understanding of Cell Biology.Journal of proteome research · 2024Review
- Machine learning approaches for spatial omics data analysis in digital pathology: tools and applications in genitourinary oncology.Frontiers in oncology · 2024Review
- Deep and fast label-free Dynamic Organellar Mapping.Nature communications · 2023Article
- SubCellBarCode: integrated workflow for robust spatial proteomics by mass spectrometry.Nature protocols · 2022Review
- A Method to Estimate the Distribution of Proteins across Multiple Compartments Using Data from Quantitative Proteomics Subcellular Fractionation Experiments.Journal of proteome research · 2022Article
- Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle.Cell death & disease · 2022Article
- PSL-LCCL: a resource for subcellular protein localization in liver cancer cell line SK_HEP1.Database : the journal of biological databases and curation · 2022Article
- Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution.Nature communications · 2021Article
- Subcellular proteomics.Nature reviews. Methods primers · 2021Article
- Organellar Maps Through Proteomic Profiling - A Conceptual Guide.Molecular & cellular proteomics : MCP · 2020Review
- Comparative Analysis of Quantitative Mass Spectrometric Methods for Subcellular Proteomics.Journal of proteome research · 2020Article
- Spatial proteomics: a powerful discovery tool for cell biology.Nature reviews. Molecular cell biology · 2019Review
- Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics.Nature communications · 2019Article
- Article
- Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population.Molecular & cellular proteomics : MCP · 2018Article
- Article
- High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes.PloS one · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a tool for the analysis of subcellular proteomics data, called MetaMass, based on the use of standardized lists of subcellular markers. We analyzed data from 11 studies using MetaMass, mapping the subcellular location of 5,970 proteins. Our analysis revealed large variations in the performance of subcellular fractionation protocols as well as systematic biases in protein annotation databases. The Excel and R versions of MetaMass should enhance transparency and reproducibility in subcellular proteomics.
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Registered trials
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