Evidence map›Paper›PMID 27571195›Full record

ReviewNature neuroscience2016

Improving data quality in neuronal population recordings.

Kenneth D Harris, Rodrigo Quian Quiroga, Jeremy Freeman, Spencer L Smith

Abstract readReview
In one paragraph

Review in Nature neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed.

  1. Article
  2. Detection and Removal of Hyper-synchronous Artifacts in Massively Parallel Spike Recordings.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  4. Review
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  19. Review
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kenneth D HarrisUCL Institute of Neurology, University College London, London, UK.ORCID 0000-0002-5930-6456
Rodrigo Quian QuirogaCentre for Systems Neuroscience, University of Leicester, Leicester, UK.
Jeremy FreemanHoward Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia, USA.
Spencer L SmithDepartment of Cell Biology and Physiology, UNC School of Medicine, Chapel Hill, North Carolina, USA.

Funding

Modulation of dendritic spiking in vivoR01NS091335 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRENMAN, JAY, SMITH, SPENCER LAVERE · 2015 to 2020
$2.0M
Development and function of higher visual areas in miceR01EY024294 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, SPENCER LAVERE · 2015 to 2019
$1.7M
Medical Research CouncilNEI NIH HHS R01 EY024294NINDS NIH HHS R01 NS091335Wellcome TrustWellcome Trust 100154Wellcome Trust 95668Wellcome Trust 95669
6 · The paper itself

Abstract

Understanding how the brain operates requires understanding how large sets of neurons function together. Modern recording technology makes it possible to simultaneously record the activity of hundreds of neurons, and technological developments will soon allow recording of thousands or tens of thousands. As with all experimental techniques, these methods are subject to confounds that complicate the interpretation of such recordings, and could lead to erroneous scientific conclusions. Here we discuss methods for assessing and improving the quality of data from these techniques and outline likely future directions in this field.

Indexed as

Data AccuracyAction PotentialsAnimalsBrainElectrophysiological PhenomenaHumansNerve NetNeuronsOptical Imaging

Identifiers

PMID27571195
PMCPMC5244825

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.