Evidence map›Paper›PMID 27571085›Full record

ArticleMarine drugs2016

Additional New Cytotoxic Triquinane-Type Sesquiterpenoids Chondrosterins K-M from the Marine Fungus Chondrostereum sp.

Lei Huang, Wen-Jian Lan, Rong Deng, Gong-Kan Feng, Qing-Yan Xu, Zhi-Yu Hu, Xiao-Feng Zhu, Hou-Jin Li

Abstract read
In one paragraph

Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Species Diversity and Secondary Metabolites ofMolecules (Basel, Switzerland) · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei HuangSchool of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China. marinehuangl@gmail.com.
Wen-Jian LanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. lanwj@mail.sysu.edu.cn.
Rong DengState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China. dengrong@sysucc.org.cn.
Gong-Kan FengState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China. fenggk@sysucc.org.cn.
Qing-Yan XuSchool of Life Sciences, Xiamen University, Xiamen 361102, China. xuqingyan@xmu.edu.cn.
Zhi-Yu HuSchool of Life Sciences, Xiamen University, Xiamen 361102, China. huzhiyu@xmu.edu.cn.
Xiao-Feng ZhuState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China. zhuxfeng@mail.sysu.edu.cn.
Hou-Jin LiSchool of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China. ceslhj@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By the method of ¹H NMR prescreening and tracing the diagnostic proton signals of the methyl groups, three additional new triquinane-type sesquiterpenoids-chondrosterins K-M (1-3) and the known sesquiterpenoid anhydroarthrosporone (4)-were isolated from the marine fungus Chondrostereum sp. Their structures were elucidated on the basis of MS, 1D, and 2D NMR data. Chondrosterin K is a rare hirsutane sesquiterpenoid, in which a methyl group was migrated from C-2 to C-6 and has a double bond between C-2 and C-3. Compounds 1-3 showed significant cytotoxicities against various cancer cell lines in vitro.

Indexed as

AnimalsAnthozoaAntibiotics, AntineoplasticCell Line, TumorFermentationHumansMagnetic Resonance SpectroscopyMass SpectrometryMolecular ConformationPolyporalesSeawaterSesquiterpenesSpectrometry, Mass, Electrospray IonizationAntibiotics, Antineoplasticchondrosterin Kchondrosterin Lchondrosterin MSesquiterpenesChondrostereum sp.chondrosterincytotoxicityhirsutanesesquiterpenoid

Identifiers

PMID27571085
PMCPMC5039528

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.