Evidence map›Paper›PMID 27571071›Full record

ArticleInternational journal of molecular sciences2016

Saponin-Based Nanoemulsification Improves the Antioxidant Properties of Vitamin A and E in AML-12 Cells.

Qaisra Naheed Choudhry, Mi Jeong Kim, Tae Gyun Kim, Jeong Hoon Pan, Jun Ho Kim, Sung Jin Park, Jin Hyup Lee, Young Jun Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Saponins as Natural Emulsifiers for Nanoemulsions.Journal of agricultural and food chemistry · 2022
    Review
  3. Saponins in Cancer Treatment: Current Progress and Future Prospects.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021
    Review
  4. Review
  5. Review
  6. Genome-Protecting Compounds as Potential Geroprotectors.International journal of molecular sciences · 2020
    Review
  7. Article
  8. Article
  9. Purification and Identification of a Natural Antioxidant Protein from Fertilized Eggs.Korean journal for food science of animal resources · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qaisra Naheed ChoudhryDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. qaisra@korea.ac.kr.
Mi Jeong KimDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. micaella76@gmail.com.
Tae Gyun KimDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. summermoon@korea.ac.kr.
Jeong Hoon PanDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. jh_pan@korea.ac.kr.
Jun Ho KimDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. phillip@korea.ac.kr.
Sung Jin ParkDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. timothypsj@hanmail.net.
Jin Hyup LeeDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. jinhyuplee@korea.ac.kr.
Young Jun KimDepartment of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea. yk46@korea.ac.kr.
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our work aimed to investigate the protective effects of saponin-based nanoemulsions of vitamin A and E against oxidative stress-induced cellular damage in AML-12 cells. Saponin nanoemulsions of vitamin A (SAN) and vitamin E (SEN) were prepared by high-pressure homogenization and characterized in terms of size, zeta potential, and polydispersity index. SEN and SAN protect AML-12 cells against oxidative stress-induced cellular damage more efficiently via scavenging reactive oxygen species (ROS), and reducing DNA damage, protein carbonylation, and lipid peroxidation. These results provide valuable information for the development of nanoemulsion-based delivery systems that would improve the antioxidant properties of vitamin A and E.

Indexed as

AntioxidantsEmulsionsHepatocytesHumansHydrogen PeroxideNanostructuresOxidative StressReactive Oxygen SpeciesSaponinsVitamin AVitamin EAntioxidantsEmulsionsHydrogen PeroxideReactive Oxygen SpeciesSaponinsVitamin AVitamin Eantioxidant capacitynanoemulsificationsaponinvitamin Avitamin E

Identifiers

PMID27571071
PMCPMC5037686
OpenAlexW2515659535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.