ReviewMolecules (Basel, Switzerland)2016
Cardiac Meets Skeletal: What's New in Microfluidic Models for Muscle Tissue Engineering.
Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Advanced Microfluidic Models of Cancer and Immune Cell Extravasation: A Systematic Review of the Literature.Frontiers in bioengineering and biotechnology · 2020Pooled it
- Review
- Muscle fibre morphometric analysis (MusMA) correlates with muscle function and cardiovascular risk prognosis.International journal of experimental pathology · 2024Article
- Tumor heterogeneity: preclinical models, emerging technologies, and future applications.Frontiers in oncology · 2023Review
- Organs-on-Chips Platforms Are Everywhere: A Zoom on Biomedical Investigation.Bioengineering (Basel, Switzerland) · 2022Review
- Will microfluidics enable functionally integrated biohybrid robots?Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Review
- Bizonal cardiac engineered tissues with differential maturation features in a mid-throughput multimodal bioreactor.iScience · 2022Article
- Assessing the influence of perfusion on cardiac microtissue maturation: A heart-on-chip platform embedding peristaltic pump capabilities.Biotechnology and bioengineering · 2021Article
- Investigations on T cell transmigration in a human skin-on-chip (SoC) model.Lab on a chip · 2021Article
- Organ-on-a-chip: recent breakthroughs and future prospects.Biomedical engineering online · 2020Review
- Microfluidic technologies to engineer mesenchymal stem cell aggregates-applications and benefits.Biophysical reviews · 2020Review
- Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.Micromachines · 2019Article
- 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration.International journal of nanomedicine · 2019Review
- A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac microtissues.APL bioengineering · 2018Article
- Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms.Future science OA · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last few years microfluidics and microfabrication technique principles have been extensively exploited for biomedical applications. In this framework, organs-on-a-chip represent promising tools to reproduce key features of functional tissue units within microscale culture chambers. These systems offer the possibility to investigate the effects of biochemical, mechanical, and electrical stimulations, which are usually applied to enhance the functionality of the engineered tissues. Since the functionality of muscle tissues relies on the 3D organization and on the perfect coupling between electrochemical stimulation and mechanical contraction, great efforts have been devoted to generate biomimetic skeletal and cardiac systems to allow high-throughput pathophysiological studies and drug screening. This review critically analyzes microfluidic platforms that were designed for skeletal and cardiac muscle tissue engineering. Our aim is to highlight which specific features of the engineered systems promoted a typical reorganization of the engineered construct and to discuss how promising design solutions exploited for skeletal muscle models could be applied to improve cardiac tissue models and vice versa.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.