ArticleSaudi medical journal2016
Vitamin D deficiency and biochemical variations among urban Saudi adolescent girls according to season.
Article in Saudi medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Association of bone mineralization markers with dietary nutrient intake in adolescents with and without biochemical osteomalacia.Frontiers in nutrition · 2023Article
- Establishing the Prevalence of Osteomalacia in Arab Adolescents Using Biochemical Markers of Bone Health.Nutrients · 2022Article
- Knowledge and Attitudes towards Vitamin D among Health Educators in Public Schools in Jeddah, Saudi Arabia: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2022Article
- Article
- Impact of Nutritional and Environmental Factors on Vitamin D DeficiencyAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Article
- Vitamin D in the Middle East and North Africa.Bone reports · 2018Article
- Vitamin D status correction in Saudi Arabia: an experts' consensus under the auspices of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis, and Musculoskeletal Diseases (ESCEO).Archives of osteoporosis · 2017Article
- Serum 25-hydroxyvitamin D and bone turnover markers in Palestinian postmenopausal osteoporosis and normal women.Archives of osteoporosis · 2017Article
- Prevalence and Predictors of Hypovitaminosis D Among Female University Students in Tabuk, Saudi Arabia.Clinical medicine insights. Women's health · 2017Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine seasonal variations in the vitamin D status of Saudi adolescent girls in Riyadh, Kingdom of Saudi Arabia (KSA) and its effect in biochemical and clinical characteristics.
methodsIn this prospective study, a total of 2000 Saudi females aged 12-18 years from different schools in Riyadh, KSA participated and submitted a generalized questionnaire with clinical information. Fasting blood samples were obtained in 1618 subjects for the winter season (December to February) and only 499 subjects returned to submit fasting blood samples for the summer season (June-August). Circulating serum 25(OH)D, parathyroid hormone (PTH), and other biomarkers of bone remodeling were measured during both seasons.
resultsVitamin D deficiency (serum 25(OH)D less than 25 nmol/L) was significantly higher during summer than winter (63.5% versus 40.8%; p less than 0.001). Mean serum PTH was also significantly higher during summer than winter (p less than 0.01). In all subjects, serum PTH showed a significant inverse association with 25(OH)D at levels below 40 nmol/L (r=-0.21; p less than 0.001). The prevalence of subjects having clinical and metabolic manifestations suggestive of osteomalacia was 2.13% (N=33 out of 1548).
conclusionSeasonal variations in the vitamin D status of Saudi adolescent females significantly modifies biochemical parameters as response to vitamin D status change. In the meantime, heightened public health awareness should be given to populations at higher risk for vitamin D deficiency.
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