Evidence map›Paper›PMID 27570845›Full record

ArticleContemporary clinical trials communications2016

Mexican-American perspectives on participation in clinical trials: A qualitative study.

Mariana Arevalo, Natalia I Heredia, Sarah Krasny, Maria L Rangel, Leticia A Gatus, Lorna H McNeill, Maria E Fernandez

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical trials communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 53 citations in OpenAlex.

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  14. Impact of white matter hyperintensity volume on cognition among US Mexican American adults.Journal of the International Neuropsychological Society : JINS · 2024
    Article
  15. Article
  16. Article
  17. Increasing Diversity of Patients in Radiation Oncology Clinical Trials.International journal of radiation oncology, biology, physics · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariana ArevaloUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
Natalia I HerediaUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
Sarah KrasnyUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
Maria L RangelUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
Leticia A GatusUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
Lorna H McNeillThe University of Texas MD Anderson Cancer Center, Department of Health Disparities Research, 1400 Pressler St., Houston, TX 77030-3906, USA.
Maria E FernandezUniversity of Texas Health Science Center at Houston, School of Public Health, 7000 Fannin Street, Houston, TX 77030, USA.
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
BEHAVIORAL SCIENCE EDUCATION--CANCER PREVENTION/CONTROLR25CA057712 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MULLEN, PATRICIA DOLAN · 1992 to 2017
$8.6M
Training ProgramU54CA153505 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BASEN-ENGQUIST, KAREN M, FERNANDEZ, MARIA EULALIA · 2010 to 2015
$4.7M
A Faith-Based Partnership to Address Obesity in African American familiesR13HD080934 · NICHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MCNEILL, LORNA H. · 2014 to 2016
$88k
NCATS NIH HHS UL1 TR000371NCI NIH HHS R25 CA057712NCI NIH HHS U54 CA153505NICHD NIH HHS R13 HD080934
6 · The paper itself

Abstract

Clinical trials are essential to advancing knowledge to reduce disease morbidity and mortality; however, ethnic and racial minorities remain under-represented in those studies. We explored knowledge and perceptions of clinical trials among Mexican-Americans in Texas. We conducted focus groups (N = 128) stratified by gender, language preference, and geographical location. This paper presents four emergent, primary themes: 1) knowledge and understanding of clinical trials, 2) fears and concerns about participating, 3) perceived benefits of participating, and 4) incentives to participate. Results suggest that lack of knowledge and understanding of clinical trials leads to misunderstanding about research, including fears and lack of trust. Participants indicated that fears related to perceived experimentation, harm, immigration status, and lack of clinical trial opportunities within their communities were barriers to participation. On the other hand, free healthcare access, helping family members in the future, and monetary incentives could facilitate participation. We also found differences across themes by language, gender, and place of residence. Findings from our study could inform the development of interventions to enhance recruitment of Mexican-American participants into clinical trials.

Indexed as

GenderGeographical locationHispanicLanguageLatinoTherapeutic misconception

Identifiers

PMID27570845
PMCPMC4999069
OpenAlexW2475335885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.