Evidence map›Paper›PMID 27570807›Full record

ArticleData in brief2016

Data on IL-6 c.-174 G>C genotype and allele frequencies in patients with coronary heart disease in dependence of cardiovascular outcome.

Stefan Reichert, Axel Schlitt, Ann-Christin Benten, Britt Hofmann, Hans-Günter Schaller, Susanne Schulz

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01045070 (Periodontitis and Its Microbiological Agents as Prognostic Factors in Patients With Coronary Heart Disease), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01045070 completednot on this map

Periodontitis and Its Microbiological Agents as Prognostic Factors in Patients With Coronary Heart Disease

TypeobservationalSponsorMartin-Luther-Universität Halle-WittenbergRan2009 to 2012Enrolled960ConditionsPeriodontitis, Coronary Heart Disease
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stefan ReichertDepartment of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
Axel SchlittDepartment of Cardiology, Paracelsus-Harz-Clinic Bad Suderode, Quedlinburg, Germany; Department of Internal Medicine III, Martin-Luther-University Halle-Wittenberg, Germany.
Ann-Christin BentenDepartment of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
Britt HofmannDepartment of Cardiothoracic Surgery, Heart Centre of the University Clinics Halle (Saale), Martin-Luther-University Halle-Wittenberg, Germany.
Hans-Günter SchallerDepartment of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
Susanne SchulzDepartment of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this data article we present data on the distribution of alleles and genotypes of the interleukin (IL)-6 c.-174 G>C polymorphism (rs 1800795) in patients with coronary heart disease (CHD) in dependence of the incidence of new cardiovascular events (combined endpoint: myocardial infarction, stroke/TIA, cardiac death, death according to stroke) within three years follow-up. Moreover, we investigated putative associations between individual expression of IL-6 genotypes and IL-6 serum level. This investigation is a subanalysis of the article entitled "The Interleukin 6 c.-174 CC genotype is a predictor for new cardiovascular events in patients with coronary heart disease within three years follow-up" (ClinicalTrials.gov identifier: NCT01045070) (Reichert et al., 2016) [1].

Indexed as

Coronary heart diseaseIL-6 polymorphismIL-6 serum levelNew cardiovascular events

Identifiers

PMID27570807
PMCPMC4990635
OpenAlexW2496667719

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.