Evidence map›Paper›PMID 27570728›Full record

ArticleCurrent addiction reports2016

Emerging Pharmacologic Treatments for Adolescent Substance Use: Challenges and New Directions.

Robert Miranda, Hayley Treloar

Open access · greenAbstract read
In one paragraph

Article in Current addiction reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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  5. Article
  6. Review
  7. Pharmacological Treatment of Youth Substance Use Disorders.Journal of child and adolescent psychopharmacology · 2019
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Robert MirandaCenter for Alcohol and Addiction Studies, Brown University.
Hayley TreloarCenter for Alcohol and Addiction Studies, Brown University.
Brown University · USJohn Brown University · US

Funding

NALTREXONE, CRAVING AND DRINKING: ECOLOGICAL ASSESSMENTR01AA007850 · NIAAA · BROWN UNIVERSITY · PI MIRANDA, ROBERT · 1988 to 2015
$8.4M
NIAAA NIH HHS R01 AA007850
6 · The paper itself

Abstract

Adolescence is a key period in the development of substance use and misuse. Substance use typically begins during adolescence and prevalence rates for many substance use disorders peak before age 21 years. Yet, despite clinical demand, treatments for youth rely almost entirely on psychosocial interventions that yield only modest benefit. One potential way to improve treatment effects is to augment the best available psychosocial interventions with pharmacotherapy. Although pharmacotherapy research has advanced care for adults with substance use disorders, no medication is indicated for adolescents and controlled trials with teenagers are scant. Optimizing treatments for youth will require closing this important gap in medication development research. In this paper we review the paucity of pharmacotherapy research for adolescent substance misuse, and we discuss how we can leverage human laboratory paradigms and technology to advance our understanding regarding if and how medications may improve treatment options for youths.

Indexed as

AdolescentsEcological Momentary AssessmentHuman LaboratoryMedicationPharmacotherapyReviewSubstance Use

Identifiers

PMID27570728
PMCPMC4996479
OpenAlexW2317040133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.