Reduction of blurring in broadband volume holographic imaging using a deconvolution method.

Yanlu Lv, Xuanxuan Zhang, Dong Zhang, Lin Zhang, Yuan Luo, Jianwen Luo

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Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Yanlu LvDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.

Xuanxuan ZhangDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.

Dong ZhangDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.

Lin ZhangDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.

Yuan LuoInstitute of Medical Device and Imaging, National Taiwan University, Taipei 10051, Taiwan.

Jianwen LuoDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China; Center for Biomedical Imaging Research, Tsinghua University, Beijing 100084, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Volume holographic imaging (VHI) is a promising biomedical imaging tool that can simultaneously provide multi-depth or multispectral information. When a VHI system is probed with a broadband source, the intensity spreads in the horizontal direction, causing degradation of the image contrast. We theoretically analyzed the reason of the horizontal intensity spread, and the analysis was validated by the simulation and experimental results of the broadband impulse response of the VHI system. We proposed a deconvolution method to reduce the horizontal intensity spread and increase the image contrast. Imaging experiments with three different objects, including bright field illuminated USAF test target and lung tissue specimen and fluorescent beads, were carried out to test the performance of the proposed method. The results demonstrated that the proposed method can significantly improve the horizontal contrast of the image acquire by broadband VHI system.

Indexed as

(010.7295) Visibility and imaging(090.7330) Volume gratings(100.1830) Deconvolution(110.6955) Tomographic imaging(170.3880) Medical and biological imaging

Identifiers

PMID27570703

DOI10.1364/BOE.7.003124

PMCPMC4986819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.