ArticleBiomedical optics express2016
Tissue diagnosis using power-sharing multifocal Raman micro-spectroscopy and auto-fluorescence imaging.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Spatially multiplexed random-access Raman probe for in vivo tissue measurements.Biomedical optics express · 2026Article
- Rapid hyperspectral Raman imaging of cells with depthwise separable 3D MultiResU-Net.iScience · 2025Article
- Intraoperative spectroscopic evaluation of sentinel lymph nodes in breast cancer surgery.Breast cancer research and treatment · 2024Article
- From Vibrations to Visions: Raman Spectroscopy's Impact on Skin Cancer Diagnostics.Journal of clinical medicine · 2023Review
- Quantification of Drugs in Brain and Liver Mimetic Tissue Models Using Raman Spectroscopy.Applied spectroscopy · 2023Article
- High-throughput line-illumination Raman microscopy with multislit detection.Biomedical optics express · 2023Article
- Deep Multi-Objective Learning from Low-Dose CT for Automatic Lung-RADS Report Generation.Journal of personalized medicine · 2022Article
- Review
- Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery.Biomedical optics express · 2021Article
- Raman Microscopy: Progress in Research on Cancer Cell Sensing.Sensors (Basel, Switzerland) · 2020Review
- Fluorescence imaging and Raman spectroscopy applied for the accurate diagnosis of breast cancer with deep learning algorithms.Biomedical optics express · 2020Article
- Raman Spectroscopy Study of Curvature-Mediated Lipid Packing and Sorting in Single Lipid Vesicles.Biophysical journal · 2019Article
- Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery.Breast cancer research : BCR · 2018Article
- Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery.Biomedical optics express · 2017Article
- Label-Free Raman Hyperspectral Imaging of Single Cells Cultured on Polymer Substrates.Applied spectroscopy · 2017Article
- Proof-of-concept Raman spectroscopy study aimed to differentiate thyroid follicular patterned lesions.Scientific reports · 2017Article
- Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy.Sensors (Basel, Switzerland) · 2017Review
- Rapid and accurate peripheral nerve imaging by multipoint Raman spectroscopy.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
We describe a multifocal Raman micro-spectroscopy detection method based on a digital micromirror device, which allows for simultaneous "power-sharing" acquisition of Raman spectra from ad hoc sampling points. As the locations of the points can be rapidly updated in real-time via software control of a liquid-crystal spatial light modulator (LC-SLM), this technique is compatible with automated adaptive- and selective-sampling Raman spectroscopy techniques, the latter of which has previously been demonstrated for fast diagnosis of skin cancer tissue resections. We describe the performance of this instrument and show examples of multiplexed measurements on a range of test samples. Following this, we show the feasibility of reducing measurement time for power-shared multifocal Raman measurements combined with confocal auto-fluorescence imaging to provide guided diagnosis of tumours in human skin samples.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.