ArticleBiomedical optics express2016
In vivo demonstration of reflection artifact reduction in photoacoustic imaging using synthetic aperture photoacoustic-guided focused ultrasound (PAFUSion).
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- The confounding effects of skin colour in photoacoustic imaging.Nature communications · 2026Article
- Distribution-informed and wavelength-flexible data-driven photoacoustic oximetry.Journal of biomedical optics · 2024Article
- Photoacoustic Imaging of Near-Bone Soft Tissue Vasculature in an ex vivo Phantom.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Feasibility of photoacoustic-guided ultrasound treatment for port wine stains.Lasers in surgery and medicine · 2023Article
- Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.Journal of biomedical optics · 2021Review
- Photostability of Contrast Agents for Photoacoustics: The Case of Gold Nanorods.Nanomaterials (Basel, Switzerland) · 2021Review
- Portable and Affordable Light Source-Based Photoacoustic Tomography.Sensors (Basel, Switzerland) · 2020Review
- Spatial weight matrix in dimensionality reduction reconstruction for micro-electromechanical system-based photoacoustic microscopy.Visual computing for industry, biomedicine, and art · 2020Article
- Photoacoustic imaging for surgical guidance: Principles, applications, and outlook.Journal of applied physics · 2020Article
- Reducing artifacts in photoacoustic imaging by using multi-wavelength excitation and transducer displacement.Biomedical optics express · 2019Article
- Sparsity-based photoacoustic image reconstruction with a linear array transducer and direct measurement of the forward model.Journal of biomedical optics · 2018Article
- Adjustable photoacoustic tomography probe improves light delivery and image quality.Photoacoustics · 2018Article
- Impact of depth-dependent optical attenuation on wavelength selection for spectroscopic photoacoustic imaging.Photoacoustics · 2018Article
- Generation and Analysis of Ultrasound Images Using Plane Wave and Sparse Arrays Techniques.Sensors (Basel, Switzerland) · 2018Article
- Reflection artifact identification in photoacoustic imaging using multi-wavelength excitation.Biomedical optics express · 2018Article
- Rapid scanning wide-field clutter elimination in epi-optoacoustic imaging using comb LOVIT.Photoacoustics · 2018Article
- Handheld Real-Time LED-Based Photoacoustic and Ultrasound Imaging System for Accurate Visualization of Clinical Metal Needles and Superficial Vasculature to Guide Minimally Invasive Procedures.Sensors (Basel, Switzerland) · 2018Article
- All-optical extravascular laser-ultrasound and photoacoustic imaging of calcified atherosclerotic plaque in excised carotid artery.Photoacoustics · 2018Article
- Virtual acoustics in inhomogeneous media with single-sided access.Scientific reports · 2018Article
- Photoacoustic reflection artifact reduction using photoacoustic-guided focused ultrasound: comparison between plane-wave and element-by-element synthetic backpropagation approach.Biomedical optics express · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reflection artifacts caused by acoustic inhomogeneities are a critical problem in epi-mode biomedical photoacoustic imaging. High light fluence beneath the probe results in photoacoustic transients, which propagate into the tissue and reflect back from echogenic structures. These reflection artifacts cause problems in image interpretation and significantly impact the contrast and imaging depth. We recently proposed a method called PAFUSion (Photoacoustic-guided focused ultrasound) to identify such reflection artifacts in photoacoustic imaging. In its initial version, PAFUSion mimics the inward-travelling wavefield from small blood vessel-like PA sources by applying ultrasound pulses focused towards these sources, and thus provides a way to identify the resulting reflection artifacts. In this work, we demonstrate reduction of reflection artifacts in phantoms and in vivo measurements on human volunteers. In view of the spatially distributed PA sources that are found in clinical applications, we implemented an improved version of PAFUSion where photoacoustic signals are backpropagated to imitate the inward travelling wavefield and thus the reflection artifacts. The backpropagation is performed in a synthetic way based on the pulse-echo acquisitions after transmission on each single element of the transducer array. The results provide a direct confirmation that reflection artifacts are prominent in clinical epi-photoacoustic imaging, and that PAFUSion can strongly reduce these artifacts to improve deep-tissue photoacoustic imaging.
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