Evidence map›Paper›PMID 27570688›Full record

ArticleBiomedical optics express2016

Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter.

Hsiang-Chieh Lee, Osman Oguz Ahsen, Kaicheng Liang, Zhao Wang, Cody Cleveland, Lucas Booth, Benjamin Potsaid, Vijaysekhar Jayaraman, Alex E Cable, Hiroshi Mashimo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Towards OCT-Guided Endoscopic Laser Surgery-A Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  8. A review of low-cost and portable optical coherence tomography.Progress in biomedical engineering (Bristol, England) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?Applied sciences (Basel, Switzerland) · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hsiang-Chieh LeeDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA.
Osman Oguz AhsenDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA.
Kaicheng LiangDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA.
Zhao WangDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA.
Cody ClevelandKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA; Brigham and Women's Hospital, Boston MA, USA.
Lucas BoothKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA.
Benjamin PotsaidDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA; Advanced Imaging Group, Thorlabs Inc., Newton NJ, USA.
Vijaysekhar JayaramanPraevium Research Inc., Santa Barbara CA, USA.
Alex E CableAdvanced Imaging Group, Thorlabs Inc., Newton NJ, USA.
Hiroshi MashimoHarvard Medical School, Boston, MA, USA; Veterans Affairs Boston Healthcare System, Boston MA, USA.
Robert LangerKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA.
Giovanni TraversoKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA; Brigham and Women's Hospital, Boston MA, USA; Harvard Medical School, Boston, MA, USA.
James G FujimotoDepartment of Electrical Engineering & Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA.
Praevium Research (United States) · US

Funding

Novel Optical Diagnostics with Optical Coherence TomographyR01EY011289 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI JAMES G FUJIMOTO · 1995 to 2026
$9.5M
CONTROLLED RELEASE OF MACROMOLECULESR01EB000244 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL, TRAVERSO, CARLO GIOVANNI · 2002 to 2021
$6.1M
OPTICAL BIOPSY USING OPTICAL COHERENCE TOMOGRAPHYR01CA075289 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FUJIMOTO, JAMES G, MASHIMO, HIROSHI · 1997 to 2018
$4.8M
Controlled Release of MacromoleculesR37EB000244 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL · 2008 to 2017
$3.9M
Ultrahigh speed and resolution OCT/OCM using broadband swept VCSEL technologyR44CA101067 · NCI · PRAEVIUM RESEARCH, INC. · PI JAYARAMAN, VIJAYSEKHAR · 2003 to 2012
$2.9M
Intraoperative real time breast cancer margin assessment with nonlinear microscopR01CA178636 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CONNOLLY, JAMES, FUJIMOTO, JAMES G · 2013 to 2018
$1.7M
VCSEL technology for ultrahigh speed OCT retinal and anterior eye imagingR44EY022864 · NEI · PRAEVIUM RESEARCH, INC. · PI JAYARAMAN, VIJAYSEKHAR · 2012 to 2014
$1.1M
NCI NIH HHS R01 CA075289NCI NIH HHS R01 CA178636NCI NIH HHS R44 CA101067NEI NIH HHS R01 EY011289NEI NIH HHS R44 EY022864NIBIB NIH HHS R01 EB000244NIBIB NIH HHS R37 EB000244
6 · The paper itself

Abstract

We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 µm axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 frames per second (fps) with a ~30 µm (FWHM) spot size. Volumetric imaging is achieved by proximal pullback of the micromotor assembly within the balloon at 1.5 mm/sec. Volumetric data consisting of 4200 circumferential images of 5,000 A-scans each over a 2.6 cm length, covering a ~13 cm(2) area is acquired in <18 seconds. A non-rigid image registration algorithm is used to suppress motion artifacts from non-uniform rotational distortion (NURD), cardiac motion or respiration. En face OCT images at various depths can be generated. OCT angiography (OCTA) is computed using intensity decorrelation between sequential pairs of circumferential scans and enables three-dimensional visualization of vasculature. Wide area volumetric OCT and OCTA imaging of the swine esophagus in vivo is demonstrated.

Indexed as

(110.6880) Three-dimensional image acquisition(170.2150) Endoscopic imaging(170.2680) Gastrointestinal(170.3880) Medical and biological imaging(170.4500) Optical coherence tomography

Identifiers

PMID27570688
PMCPMC4986804
OpenAlexW2473558214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.