Evidence map›Paper›PMID 27570679›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2016

Identifying Family History and Substance Use Associations for Adult Epilepsy from the Electronic Health Record.

Yan Wang, Elizabeth S Chen, Ilo Leppik, Serguei Pakhomov, Indra Neil Sarkar, Genevieve B Melton

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan WangInstitute for Health Informatics, University of Minnesota, Minneapolis, MN;
Elizabeth S ChenCenter for Biomedical Informatics, Brown University, Providence, RI.
Ilo LeppikCollege of Pharmacy, and Medical School, University of Minnesota, Minneapolis, MN;; Medical School, University of Minnesota, Minneapolis, MN;
Serguei PakhomovInstitute for Health Informatics, University of Minnesota, Minneapolis, MN;; College of Pharmacy, and Medical School, University of Minnesota, Minneapolis, MN;
Indra Neil SarkarCenter for Biomedical Informatics, Brown University, Providence, RI.
Genevieve B MeltonInstitute for Health Informatics, University of Minnesota, Minneapolis, MN;; Medical School, University of Minnesota, Minneapolis, MN;

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Natural language processing for clinical and translational researchR01GM102282 · NIGMS · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, PAKHOMOV, SERGUEI VS · 2013 to 2016
$2.5M
Discovery and Visualization of New Information from Clinical Reports in the EHRR01HS022085 · AHRQ · UNIVERSITY OF MINNESOTA · PI MELTON-MEAUX, GENEVIEVE B · 2013 to 2016
$1.9M
Leveraging the EHR to Collect and Analyze Social, Behavioral & Familial FactorsR01LM011364 · NLM · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHEN, ELIZABETH S., MELTON-MEAUX, GENEVIEVE B · 2012 to 2015
$1.4M
AHRQ HHS R01 HS022085NCATS NIH HHS UL1 TR000114NIGMS NIH HHS R01 GM102282NLM NIH HHS R01 LM011364
6 · The paper itself

Abstract

Epilepsy is a prevalent chronic neurological disorder afflicting about 50 million people worldwide. There is evidence of a strong relationship between familial risk factors and epilepsy, as well as associations with substance use. The goal of this study was to explore the interactions between familial risk factors and substance use based on structured data from the family and social history modules of an electronic health record system for adult epilepsy patients. A total of 8,957patients with 38,802 family history entries and 8,822 substance use entries were gathered and mined for associations at different levels of granularity for three age groupings (>18, 18-64, and ≥65 years old). Our results demonstrate the value of an association rule mining approach to validate knowledge of familial risk factors. The preliminary findings also suggest that substance use does not demonstrate significant association between social and familial risk factors for epilepsy.

Identifiers

PMID27570679
PMCPMC5001738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.