Evidence map›Paper›PMID 27570674›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2016

PALME: PAtients Like My gEnome.

Lichang Wang, Yong Fang, Dima Aref, Suyash Rathi, Li Shen, Xiaoqian Jiang, Shuang Wang

Abstract read
PubMed Full text at PMC
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lichang WangCollege of Information Engineering, Northwest A&F University, Yangling, Shaanxi, China.
Yong FangCollege of Information Engineering, Northwest A&F University, Yangling, Shaanxi, China.
Dima ArefNew Jersey Institute of Technology, Newark, New Jersey.
Suyash RathiElectrical Engineering & Computer Science, Syracuse University, Syracuse, New York.
Li ShenInstitute of Biological Sciences and Biotechnology, Donghua University, Shanghai, China;
Xiaoqian JiangDepartment of Biomedical Informatics, University of California San Diego, La Jolla, California.
Shuang WangDepartment of Biomedical Informatics, University of California San Diego, La Jolla, California.

Funding

iDASH: Integrating Data for Analysis, Anonymization, and SharingU54HL108460 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2015
$19.1M
iCONCUR: informed CONsent for Clinical data and biosample Use for ResearchR01HG008802 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN, KIM, HYEON-EUI · 2015 to 2017
$1.3M
Protection of Records: Privacy (PReP) Technology for Medical ResearchR00LM011392 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN · 2013 to 2015
$650k
Protecting the pRivacy Of Genomes in REsearch StudieS (PROGRESS)R00HG008175 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, SHUANG · 2016 to 2018
$527k
Protect Privacy of Healthcare Data in the CloudR21LM012060 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN · 2014 to 2015
$376k
Protecting the pRivacy Of Genomes in Research StudieS (PROGRESS)K99HG008175 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, SHUANG · 2014 to 2015
$100k
NHGRI NIH HHS K99 HG008175NHGRI NIH HHS R00 HG008175NHGRI NIH HHS R01 HG008802NHLBI NIH HHS U54 HL108460NLM NIH HHS R00 LM011392NLM NIH HHS R21 LM012060
6 · The paper itself

Abstract

PAtients Like My gEnome (PALME) is a webservice that matches patients based on their genome and healthcare profiles. We support two types of inputs: (1) dual query (a variant + phenotype), and (2) genome sequences. For the first type of queries, we will show the patient profile matching the inputs. For the second type of queries, we will calculate similarity (based on Hamming distance) and show the distribution of phenotypes of similar patients given the input sequences of a target patient. Using the publicly available Personal Genome Project (PGP) dataset, we retrieved 4,360 patients' profiles along with their genome data, medical conditions, and treatments. We used a subset of these profiles to build PALME to be an interactive system to support healthcare profile matching. PALME is designed not only for biomedical researchers to support their studies on human genome but also for individuals to explore their own genetics and health. The webservice is accessible at (http://pgp.ucsd-dbmi.org:3838/GenAnaly/PatientGen/#) and the demo videos are available at (https://youtu.be/ycP0rXQizlc).

Identifiers

PMID27570674
PMCPMC5001758

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.