Evidence map›Paper›PMID 27570669›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2016

A Data Mining Approach to Determine Sepsis Guideline Impact on Inpatient Mortality and Complications.

Lisiane Pruinelli, Pranjul Yadav, Andrew Hangsleben, Jakob Johnson, Sanjoy Dey, Maribet McCarty, Vipin Kumar, Connie W Delaney, Michael Steinbach, Bonnie L Westra and 1 more

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Frequent Causal Pattern Mining: A Computationally Efficient Framework For Estimating Bias-Corrected Effects.Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data · 2019
    Article
  3. A Framework for Visualizing Data Quality for Predictive Models and Clinical Quality Measures.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lisiane PruinelliSchool of Nursing, University of Minnesota, Minneapolis, MN;
Pranjul YadavDepartment of Computer Science & Engineering, University of Minnesota, Minneapolis, MN;
Andrew HangslebenDepartment of Computer Science & Engineering, University of Minnesota, Minneapolis, MN;
Jakob JohnsonDepartment of Computer Science & Engineering, University of Minnesota, Minneapolis, MN;
Sanjoy DeyIBM T. J. Watson Research Center, White Plains, NY;
Maribet McCartyHennepin County Medical Center, Minneapolis, MN;
Vipin KumarDepartment of Computer Science & Engineering, University of Minnesota, Minneapolis, MN;
Connie W DelaneySchool of Nursing, University of Minnesota, Minneapolis, MN;
Michael SteinbachDepartment of Computer Science & Engineering, University of Minnesota, Minneapolis, MN;
Bonnie L WestraSchool of Nursing, University of Minnesota, Minneapolis, MN;; Institute for Health Informatics, University of Minnesota, Minneapolis, MN;
György J SimonMayo Clinic, Rochester, MN.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
UNIVERSITY OF MINNESOTA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UMN CTSI)UL1RR033183 · NCRR · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2011 to 2011
$8.9M
NCATS NIH HHS UL1 TR000114NCRR NIH HHS UL1 RR033183
6 · The paper itself

Abstract

Sepsis incidents have doubled from 2000 through 2008, and hospitalizations for these diagnoses have increased by 70%. The use of the Surviving Sepsis Campaign (SSC) guidelines can lead to earlier diagnosis and treatment; however, the effectiveness of the SSC guidelines in preventing complications for this population is unclear. The overall purpose of this study was to apply SSC guideline recommendations to EHR data for patients with severe sepsis or septic shock and determine guideline compliance as well as its impact on inpatient mortality and sepsis complications. Propensity Score Matching in conjuction with Bootstrap Simulation were used to match patients with and without exposure to the SSC recommendations. Findings showed that EHR data could be used to estimate compliance with SSC recommendations as well as the effect of compliance on outcomes. Compliance with guideline recommendations ranged from 9% to 100%. For individual recommendations with sufficient data, association with outcomes varied. Checking lactate influenced four outcomes; however, two were negative and two positive. Use of a ventilator for patients with respiratory distress had a positive association with three outcomes.

Identifiers

PMID27570669
PMCPMC5001751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.