Evidence map›Paper›PMID 27570625›Full record

ArticleEnvironmental science. Nano2016

Carcinogenic Potential of High Aspect Ratio Carbon Nanomaterials.

Sudjit Luanpitpong, Liying Wang, Donna C Davidson, Heimo Riedel, Yon Rojanasakul

Abstract read
In one paragraph

Article in Environmental science. Nano, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The asbestos-carbon nanotube analogy: An update.Toxicology and applied pharmacology · 2018
    Review
  6. Article
  7. Article
  8. Article
  9. Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells.American journal of physiology. Lung cellular and molecular physiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sudjit LuanpitpongSiriraj Center of Excellence for Stem Cell Research, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand; Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.
Liying WangAllergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Donna C DavidsonAllergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Heimo RiedelDepartment of Biochemistry, West Virginia University, Morgantown, WV 26506, USA; Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Yon RojanasakulDepartment of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA; Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

Funding

Induction of Neoplastic Transformation and Cancer Stem Cells by Carbon NanotubesR01ES022968 · NIEHS · WEST VIRGINIA UNIVERSITY · PI ROJANASAKUL, YON · 2014 to 2019
$1.7M
Nanoparticle Fibrogenicity and Fibroblast Stem-Like CellsR01EB018857 · NIBIB · WEST VIRGINIA UNIVERSITY · PI ROJANASAKUL, YON · 2016 to 2019
$1.3M
NIBIB NIH HHS R01 EB018857NIEHS NIH HHS R01 ES022968
6 · The paper itself

Abstract

Engineered nanomaterials, including high aspect ratio carbon nanomaterials, are often commercialized without a complete human risk assessment and safety evaluation. A health concern has been raised that high aspect ratio nanomaterials such as carbon nanotubes may cause unintended health consequences, such as asbestos-like lung cancer and mesothelioma, when chronically inhaled. Considering the widespread industrial and clinical applications and the increasing incidence of human exposure to nanomaterials, it is important to address the issue of nanomaterial carcinogenicity in a timely manner. This review summarizes recent advances in nanomaterial genotoxicity and carcinogenicity with a focus on high aspect ratio carbon nanotubes, and discusses current knowledge gaps and future research directions.

Indexed as

carbon nanotubescarcinogenicitygenotoxicitypulmonary exposure

Identifiers

PMID27570625
PMCPMC4996468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.