Evidence map›Paper›PMID 27570617›Full record

ArticleRSC advances

Single Nanoparticle Plasmonic Spectroscopy for Study of the Efflux Function of Multidrug ABC Membrane Transporters of Single Live Cells.

Lauren M Browning, Kerry J Lee, Pavan K Cherukuri, Prakash D Nallathamby, Seth Warren, Jean-Michel Jault, Xiao-Hong Nancy Xu

Open access · greenAbstract read
In one paragraph

Article in RSC advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Lauren M BrowningDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Kerry J LeeDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Pavan K CherukuriDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Prakash D NallathambyDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Seth WarrenDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Jean-Michel JaultUMR5086 CNRS/UCBLyon I, MMSB-IBCP, 7 Passage du Vercors 69367 Lyon cedex 07, France.
Xiao-Hong Nancy XuDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Dominion University College · GHOld Dominion University · USUniversité Claude Bernard Lyon 1 · FR

Funding

Nanoassay for Realtime Molecular Probing ABC TransporterR01GM076440 · NIGMS · OLD DOMINION UNIVERSITY · PI XU, X. NANCY · 2006 to 2010
$1.7M
NIGMS NIH HHS R01 GM076440
6 · The paper itself

Abstract

ATP-binding cassette (ABC) membrane transporters exist in all living organisms and play key roles in a wide range of cellular and physiological functions. The ABC transporters can selectively extrude a wide variety of structurally and functionally unrelated substrates, leading to multidrug resistance. Despite extensive study, their efflux molecular mechanisms remain elusive. In this study, we synthesized and characterized purified silver nanoparticles (Ag NPs) (97 ± 13 nm in diameter), and used them as photostable optical imaging probes to study efflux kinetics of ABC membrane transporters (BmrA) of single live cells

Indexed as

ABC (BmrA) transporterAg nanoparticleBacillus subtilismultidrug resistancesingle cell imagingsingle nanoparticle plasmonic spectroscopy

Identifiers

PMID27570617
PMCPMC4999259
OpenAlexW2317414454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.