Evidence map›Paper›PMID 27570603›Full record

ArticleMalaysian family physician : the official journal of the Academy of Family Physicians of Malaysia2015

Diabetic ketoacidosis at diagnosis of type 1 diabetes mellitus in Malaysian children and adolescents.

Jyh Hong, M Y Jalaludin, B Mohamad Adam, M Z Fuziah, L L Wu, R Rasat, H Fatimah, S Premaa, U Ponnudurai, H Jamaiyah

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jyh HongMD, MRCP Department of Pediatrics, Putrajaya Hospital, Precinct 7, 62250 Putrajaya Malaysia. email yeowhuahong@hotmail.com.
M Y JalaludinMBBS, MPaeds Endocrinologist Department of Pediatrics, Faculty of Medicine, University Malaya, 59100 Kuala Lumpur, Malaysia. Email: yazidj@ummc.edu.my.
B Mohamad Adam(Corresponding author) Bsc (hons) Statistics, Biostatistics Unit, Clinical Research Centre, 50586 Kuala Lumpur Malaysia. email: adam@crc.gov.my.
M Z FuziahFuziah Md Zain MBBCh Department of Pediatrics, Putrajaya Hospital, Precinct 7, 62250 Putrajaya, Malaysia. Email: fuziah3059@yahoo.co.uk.
L L WuMRCP Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Kuala Lumpur, Malaysia. Email: looling51@yahoo.com.
R RasatMRCP Department of Paediatrics, Faculty of Medicine, University Kebangsaan Kuala Lumpur, Malaysia. Email: rahmahrasat@gmail.com.
H FatimahMBBS, MRCP, FRCP Department of Paediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.Email: fatimah17@um.edu.my.
S PremaaBsc (hons) Mathematic industry Biostatistics Unit, Clinical Research Centre, 50586 Kuala Lumpur, Malaysia. Email: premaa@crc.gov.my.
U PonnuduraiMBBS Clinical Research Centre, 50586 Kuala Lumpur, Malaysia.Email: umaponnudurai@yahoo.com.
H JamaiyahMD, MSc(Clin Epid) Clinical Epidemiology Unit, Clinical Research Centre, 50586 Kuala Lumpur, Malaysia..Email: jamaiyah@crc.gov.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic ketoacidosis (DKA) is a late presentation of newly diagnosed type 1 diabetes mellitus (DM) in children. The aim of this study was to determine the clinical characteristics of type 1 DM at presentation so that appropriate actions can be taken to promote early diagnosis.

methodsThis was a retrospective cohort review from a patient registry database. Data on all patients younger than 20 years old diagnosed with type 1 DM who had been registered with the Malaysian Diabetes in Children and Adolescents Registry (DiCARE) from its inception in 2006 until 2009 were analysed.

resultsThe study included 490 children and adolescents, out of which 57.1% were female. The mean (SD) age at diagnosis was 7.5 (3.7) years, which increased from year 2000 to 2009 [6.6 (3.3) years to 9.6 (3.5) years; p = 0.001]. An increasing percentage of DKA at diagnosis was observed from year 2000 (54.5%) to year 2009 (66.7%), which remained high and leveled between 54.5% and 75.0%. DKA was more common in patients with normal weight (p = 0.002) with no significant association with age, gender, ethnicity and status of family history of diabetes mellitus.

conclusionAn increasing trend of age at diagnosis of patients with type 1 DM was observed. Besides that, proportion of DKA at diagnosis had remained high over the past decade. This study found that normal weight was associated with status of DKA, thus more detailed investigations are required to determine the risk factors for DKA.

Indexed as

adolescentschildrenDiabetic ketoacidosistype 1 diabetes mellitus

Identifiers

PMID27570603
PMCPMC4992349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.