ArticleAnnals of Indian Academy of Neurology
Sural sensory nerve action potential: A study in healthy Indian subjects.
Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Screening for Diabetic Peripheral Neuropathy: Subjective Versus Objective Measures.The international journal of lower extremity wounds · 2026Article
- Sural/Radial Amplitude Ratio in Healthy Adults: Influence of Anatomical and Demographic Variables.Basic and clinical neuroscience · 2025Article
- Longitudinal evaluation of polyneuropathy in Parkinson's disease.Journal of neurology · 2024Article
- Could Ultrasound-Guided Stimulation of Sural Nerve Affect Nerve Conduction Study?Annals of rehabilitation medicine · 2019Article
- Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects.Annals of Indian Academy of NeurologyArticle
- Medial Plantar Sensory Nerve Action Potential: A Study for Reference Data in Indian Subjects.Annals of Indian Academy of NeurologyArticle
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Authors and funding
4 authors.
Funding
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Abstract
backgroundThe sural sensory nerve action potential (SNAP) is an important electrodiagnostic study for suspected peripheral neuropathies. Incorrect technique and unavailability of reference data can lead to erroneous conclusions.
objectivesTo establish reference data for sural SNAP in age-stratified healthy subjects at three sites of stimulation. MATERIALS AND
methodsA prospective study was conducted in 146 nerves from healthy subjects aged between 18 years and 90 years, stratified into six age groups (a = 18-30 years, b = 31-40 years, c = 41-50 years, d = 51-60 years, e = 61-70 years, and f >71 years). Sural SNAP was recorded antidromically, stimulating at three sites at distances of 14 cm, 12 cm, and 10 cm from the recording electrode. Mean - 2 standard deviation (SD) of the transformed data was used to generate reference values for amplitudes. Analysis of variance (ANOVA) test was used for inter-group and between three sites comparisons of amplitudes.
resultsThe lower limits of amplitude at 14 cm were 12.4 μV, 10.4 μV, 6.5 μV, 5.3 μV, 2.9 μV, and 1.9 μV; at 12 cm were 13.5 μV, 13.6 μV, 8.5 μV, 7.8 μV, 3.5 μV, and 2.8 μV; and at 10 cm were 16.3 μV, 16.3 μV, 11.1 μV, 10.0 μV, 4.8 μV, and 3.7 μV for groups a, b, c, d, e, and f, respectively. A statistically significant difference in amplitudes was noted from the three different sites of stimulation (P < 0.001). The amplitude differed significantly above the age of 60 years (P < 0.01) but not between groups e and f (P > 0.05).
conclusionThis study provides reference data for sural SNAP in Indian population at three different sites of stimulation along the calf in six age groups. It also shows significant variation in amplitude from the three different sites of stimulation.
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