Evidence map›Paper›PMID 27569715›Full record

ArticleJournal of the American Medical Directors Association2016

Transition Between the Timed up and Go Turn to Sit Subtasks: Is Timing Everything?

Aner Weiss, Anat Mirelman, Nir Giladi, Lisa L Barnes, David A Bennett, Aron S Buchman, Jeffrey M Hausdorff

Abstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA).The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  17. Is every-day walking in older adults more analogous to dual-task walking or to usual walking? Elucidating the gaps between gait performance in the lab and during 24/7 monitoring.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2019
    Article
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  20. Religious Orders Study and Rush Memory and Aging Project.Journal of Alzheimer's disease : JAD · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aner WeissCenter for the Study of Movement, Cognition, and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Anat MirelmanCenter for the Study of Movement, Cognition, and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Nir GiladiCenter for the Study of Movement, Cognition, and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Neurology, Sackler Faculty of Medicine, and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL.
Aron S BuchmanRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL.
Jeffrey M HausdorffCenter for the Study of Movement, Cognition, and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: jhausdor@tlvmc.gov.il.

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Racial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6M
Spinal cord and brainstem pathology contributions to late-life gait impairmentR01AG047976 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BUCHMAN, ARON S · 2015 to 2019
$2.6M
The Clinical Profile of Parkinson's Disease (PD) PathologyR01NS078009 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI BUCHMAN, ARON S · 2012 to 2016
$2.4M
NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG047976NIA NIH HHS RF1 AG022018NINDS NIH HHS R01 NS078009
6 · The paper itself

Abstract

objectiveThe Timed Up and Go (TUG), one of the most widely used tests of mobility, has been validated and associated with adverse outcomes in the community, acute care, and nursing home setting. It is composed of several distinct subtasks; however, the temporal relationship when transitioning between subtasks has not been well-studied. We tested the hypothesis that longer transition durations between the final turn to the sitting subtasks are associated with worse motor and cognitive performance in older adults.

methodsA total of 1055 participants (80.33 ± 7.57 years, 76.96% female) performed the TUG while wearing a 3-dimensional inertial sensor on their lower back. We employed a series of linear regressions to examine the association of the duration between the turn and sitting subtasks with clinical characteristics including motor and cognitive functions.

resultsParticipants employed 2 different strategies when they transitioned from turning to sitting. (1) Distinct transition strategy: 816 participants (77.34%) first completed the turn before starting to sit. The average duration between these distinct subtasks (D-interval) was 715 ± 980 ms. (2) Overlapping transition strategy: 239 participants (22.65%) started to sit before completing the turn. The average overlap duration between these tasks (O-interval) was 237 ± 269 ms. Participants who employed the distinct transition strategy were slightly younger than those who employed the overlapping transition strategy (P ≤ .013). Higher D-intervals and O-intervals were associated with worse TUG performance (P ≤ .02), with poorer motor and cognitive function, [ie, worse parkinsonian gait (P ≤ .001), lower level of perceptual speed (P ≤ .03), and with worse mobility disability (P ≤ .001)]. A longer D-interval was associated with worse gait speed and bradykinesia (P ≤ .001), whereas a longer O-interval was associated with increased rigidity (P = .004).

conclusionsOlder adults apparently employ 2 different strategies when transitioning from turning to sitting. The instrumented TUG can characterize additional gait and balance aspects that cannot be derived from traditional TUG assessments. These new measures offer novel targets for intervention to decrease the burden of late-life gait impairment.

Indexed as

Disability EvaluationTask Performance and AnalysisAgedAged, 80 and overAgingCognitive DysfunctionFemaleGeriatric AssessmentHumansMaleMonitoring, AmbulatoryMotor ActivityReaction TimeTime FactorsaccelerometersAgingcognitiondisabilityinertial sensorsTimed Up and Goturn-to-sit

Identifiers

PMID27569715
PMCPMC5004894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.