ArticleJournal of cardiovascular electrophysiology2016
Association of Left Atrial Function Index With Late Atrial Fibrillation Recurrence after Catheter Ablation.
Article in Journal of cardiovascular electrophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Left atrial function index predicts poor outcome in STEMI patients treated with percutaneous coronary intervention.Scientific reports · 2023Article
- Left atrial function index predicts poor outcomes in acute myocardial infarction patients treated with percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2023Article
- A predictive model using left atrial function and B-type natriuretic peptide level in predicting the recurrence of early persistent atrial fibrillation after radiofrequency ablation.Clinical cardiology · 2021Article
- Article
- Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study.Frontiers in cardiovascular medicine · 2019Article
- Hemodynamic impact of percutaneous left atrial appendage closure in patients with paroxysmal atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018Article
- Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study.Journal of the American Heart Association · 2018Article
- Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2017Article
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Authors and funding
14 authors at 2 institutions in 1 country.
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Abstract
introductionAlthough catheter ablation (CA) for atrial fibrillation (AF) is commonly used to improve symptoms, AF recurrence is common and new tools are needed to better inform patient selection for CA. Left atrial function index (LAFI), an echocardiographic measure of atrial mechanical function, has shown promise as a noninvasive predictor of AF. We hypothesized that LAFI would relate to AF recurrence after CA. METHODS AND
resultsAll AF patients undergoing index CA were enrolled in a prospective institutional AF Treatment Registry between 2011 and 2014. LAFI was measured post hoc from pre-ablation clinical echocardiographic images in 168 participants. Participants were mostly male (33% female), middle-aged (60 ± 10 years), obese and had paroxysmal AF (64%). Mean LAFI was 25.9 ± 17.6. Over 12 months of follow-up, 78 participants (46%) experienced a late AF recurrence. In logistic regression analyses adjusting for factors known to be associated with AF, lower LAFI remained associated with AF recurrence after CA [OR 0.04 (0.01-0.67), P = 0.02]. LAFI discriminated AF recurrence after CA slightly better than CHADS2 (C-statistic 0.60 LAFI, 0.57 CHADS2). For participants with persistent AF, LAFI performed significantly better than CHADS2 score (C statistic = 0.79 LAFI, 0.56 CHADS2, P = 0.02).
conclusionLAFI, an echocardiographic measure of atrial function, is associated with AF recurrence after CA and has improved ability to discriminate AF recurrence as compared to the CHADS-2 score, especially among persistent AF patients. Since LAFI can be calculated using standard 2D echocardiographic images, it may be a helpful tool for predicting AF recurrence.
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