Evidence map›Paper›PMID 27569652›Full record

ArticleJournal of psychiatric research2016

Lifetime history of traumatic events in a young adult Mexican American sample: Relation to substance dependence, affective disorder, acculturation stress, and PTSD.

Cindy L Ehlers, Corinne Kim, David A Gilder, Gina M Stouffer, Raul Caetano, Rachel Yehuda

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  19. Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cindy L EhlersMolecular and Cellular Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: cindye@scripps.edu.
Corinne KimMolecular and Cellular Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
David A GilderMolecular and Cellular Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
Gina M StoufferMolecular and Cellular Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
Raul CaetanoPrevention Research Center, Pacific Institute for Research and Evaluation, Oakland, CA, USA.
Rachel YehudaJames J. Peters Veterans Affairs Medical Center and Traumatic Stress Studies Division, Psychiatry Department, Mount Sinai School of Medicine, Bronx, NY 10029-6574, USA.
Scripps Research Institute · USJames J. Peters VA Medical Center · USPacific Institute For Research and Evaluation · US

Funding

Viral Vector CoreP60AA006420 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI MARISA ROBERTO · 2003 to 2026
$46.3M
SYSTEMIC NEUROPHARMACOLOGYP50AA006420 · NIAAA · SCRIPPS RESEARCH INSTITUTE · PI KOOB, GEORGE F · 1985 to 2002
$5.1M
NIAAA NIH HHS P50 AA006420NIAAA NIH HHS P60 AA006420
6 · The paper itself

Abstract

Mexican Americans comprise one of the most rapidly growing populations in the United States, and within this population, trauma and post-traumatic stress disorder (PTSD) are associated with physical and mental health problems. Therefore, efforts to delineate factors that may uniquely contribute to increased likelihood of trauma, PTSD, and substance use disorders over the lifetime in Mexican Americans are important to address health disparities and to develop treatment and prevention programs. Six hundred fourteen young adults (age 18-30 yrs) of Mexican American heritage, largely second generation, were recruited from the community and assessed with the Semi-Structured Assessment for the Genetics of Alcoholism and an acculturation stress scale. More males (51.2%) reported experiencing traumas than females (41.1%), however, a larger proportion of females received a PTSD diagnosis (15%) than males (8%). Alcohol dependence and affective disorders, but not anxiety disorders, antisocial disorders, nicotine, marijuana, or stimulant dependence, were significantly comorbid with PTSD. Endorsing higher levels of acculturation stress was also significantly associated with both trauma exposure and a diagnosis of PTSD. Logistic regression revealed that female gender, having an affective disorder, alcohol dependence, higher levels of acculturation stress, and lower levels of education were all predictors of PTSD status. Additionally, alcohol dependence generally occurred after the PTSD diagnosis in early adulthood in this high-risk population. These studies suggest that treatment and prevention efforts should particularly focus on young adult second generation Mexican American women with higher levels of acculturation stress, who may be at higher risk for PTSD, affective disorder, and alcohol dependence following trauma exposure.

Indexed as

AcculturationLife Change EventsAnalysis of VarianceChi-Square DistributionComorbidityFemaleHumansMaleMexican AmericansMood DisordersPsychiatric Status Rating ScalesStress Disorders, Post-TraumaticSubstance-Related DisordersUnited StatesYoung AdultMexican AmericanPTSDSubstance dependenceTrauma

Identifiers

PMID27569652
PMCPMC5107155
OpenAlexW2513458401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.