ArticleJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons2017
Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases.
Article in Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Pooled it
- Are medication-induced salivary changes the culprit of osteonecrosis of the jaw? A systematic review.Frontiers in medicine · 2023Pooled it
- Osteonecrosis of the jaw related to non-antiresorptive medications: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Development of a Machine Learning-Based Triage Score for Medication-Related Osteonecrosis of the Jaw in Osteoporosis Patients Undergoing Tooth Extraction.Diagnostics (Basel, Switzerland) · 2026Article
- Comments on 'Bisphosphonate and statin: adverse effects of co-medication on wound healing in in vitro models of periodontal tissues'.Acta odontologica Scandinavica · 2026Article
- Drug-related jaw osteonecrosis: a 6-year retrospective study from two centers in Argentina.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Oral Ulceration with Bone Sequestration: Key Insights for Clinicians and Their Relevance in Contemporary Clinical Practice-A Narrative Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Article
- Surgical and conservative treatment outcomes of medication-related osteonecrosis of the jaw located at tori: a retrospective study.Oral and maxillofacial surgery · 2024Article
- Maxillary Osteonecrosis Related with Herpes Zoster: A Case Report and Review of the Literature.Medicina (Kaunas, Lithuania) · 2024Review
- Case Report: single low-dose of denosumab as a trigger of MRONJ development in a patient with osteoporosis after bisphosphonate therapy.Frontiers in oral health · 2024Article
- Secukinumab Causing Medication-Related Osteonecrosis of the Jaw, in a Patient Diagnosed with Psoriasis and Rheumatoid Arthritis.Psoriasis (Auckland, N.Z.) · 2024Article
- Correlation of anti-TNF-a biological therapy with periodontal conditions and osteonecrosis in autoimmune patients: A systematic review.The Saudi dental journal · 2023Review
- Management of dental care of patients on immunosuppressive drugs for chronic immune-related inflammatory diseases: a survey of French dentists' practices.BMC oral health · 2023Review
- Review
- Osteonecrosis of the jaws in patients under osteoporosis treatment: a nine-year experience report.Archives of endocrinology and metabolism · 2023Article
- Novel modified quantitative index for cone-beam CT assessment of medication-related osteonecrosis of the jaw - comparative analysis with original index.The Saudi dental journal · 2023Article
- Quantitative indices for cone-beam CT assessment of Medication-Related Osteonecrosis of the Jaw - a scoping review.The Saudi dental journal · 2023Article
- Medication-Related Osteonecrosis of the Jaw: A Critical Narrative Review.Journal of clinical medicine · 2021Review
- The prosthodontic management of medication-related osteonecrosis of the jaw: a case report.British dental journal · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposeMedication-related osteonecrosis of the jaws (MRONJ) is a well-described complication of antiresorptive and antiangiogenic medications. Although osteonecrosis can be associated with other inciting events and medications, such as trauma, infection, steroids, chemotherapy, and coagulation disorders, these are rarely reported in the literature. MATERIALS AND
methodsThis is a six case series of MRONJ associated with medications other than antiresorptive or antiangiogenic drugs.
resultsPatient demographics, inciting event, location, stage, imaging findings, and outcome are reported.
conclusionWith the continued development and clinical use of new biologic medications for diseases such as cancer and rheumatoid arthritis, it is important to continue to evaluate their effects on the oral cavity. The degree of risk for osteonecrosis in patients taking these new classes of drugs is uncertain but warrants awareness and monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.