Evidence map›Paper›PMID 27569380›Full record

ArticleJournal of applied microbiology2016

A simple decontamination approach using hydrogen peroxide vapour for Bacillus anthracis spore inactivation.

J P Wood, M W Calfee, M Clayton, N Griffin-Gatchalian, A Touati, S Ryan, L Mickelsen, L Smith, V Rastogi

Open access · greenAbstract read
In one paragraph

Article in Journal of applied microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. HChemical engineering journal (Lausanne, Switzerland : 1996) · 2022
    Article
  3. Hydrogen Peroxide Vapor Decontamination of Hazard Group 3 Bacteria and Viruses in a Biosafety Level 3 Laboratory.Applied biosafety : journal of the American Biological Safety Association · 2022
    Article
  4. Article
  5. Decontamination Validation of a Class II Type A2 Biosafety Cabinet during Laboratory Fumigation.Applied biosafety : journal of the American Biological Safety Association · 2020
    Article
  6. Article
  7. Article
  8. Review
  9. Plasma-Activated Aerosolized Hydrogen Peroxide (aHP) in Surface Inactivation Procedures.Applied biosafety : journal of the American Biological Safety Association · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

J P WoodNational Homeland Security Research Center, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
M W CalfeeNational Homeland Security Research Center, United States Environmental Protection Agency, Research Triangle Park, NC, USA.ORCID http://orcid.org/0000-0001-6544-329X
M ClaytonARCADIS, Inc., Durham, NC, USA.
N Griffin-GatchalianARCADIS, Inc., Durham, NC, USA.
A TouatiJacobs Technology Inc., Research Triangle Park, NC, USA.
S RyanNational Homeland Security Research Center, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
L MickelsenConsequence Management Advisory Division, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
L SmithUS Army Edgewood Chemical and Biological Center, Gunpowder, MD, USA.
V RastogiUS Army Edgewood Chemical and Biological Center, Gunpowder, MD, USA.
Environmental Protection Agency · USArcadis (United States) · USJacobs (United States) · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

aimsTo evaluate the use of relatively low levels of hydrogen peroxide vapour (HPV) for the inactivation of Bacillus anthracis spores within an indoor environment. METHODS AND

resultsLaboratory-scale decontamination tests were conducted using bacterial spores of both B. anthracis Ames and Bacillus atrophaeus inoculated onto several types of materials. Pilot-scale tests were also conducted using a larger chamber furnished as an indoor office. Commercial off-the-shelf (COTS) humidifiers filled with aqueous solutions of 3 or 8% hydrogen peroxide (H

conclusionsFour- to seven-day exposures to low levels of HPV (average air concentrations of approx. 5-10 parts per million) were effective in inactivating B. anthracis spores on multiple materials. The HPV can be generated with COTS humidifiers and household H SIGNIFICANCE AND IMPACT OF THE STUDY: This simple and effective decontamination method is another option that could be widely applied in the event of a B. anthracis spore release.

Indexed as

Anti-Bacterial AgentsBacillusBacillus anthracisDecontaminationHydrogen PeroxideSpores, BacterialAnti-Bacterial AgentsHydrogen PeroxideantimicrobialsBacillus anthracisbacterial sporesbiocideshydrogen peroxide vapoursterilization

Identifiers

PMID27569380
PMCPMC6388395
OpenAlexW2516357241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.