Evidence map›Paper›PMID 27568978›Full record

ArticleOncogene2017

Sustained p16

L Palacio, V Krishnan, N L O Le, N E Sharpless, C M Beauséjour

Open access · greenAbstract read
In one paragraph

Article in Oncogene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

L PalacioCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine, Montréal, Canada.
V KrishnanCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine, Montréal, Canada.
N L O LeCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine, Montréal, Canada.
N E SharplessDepartments of Medicine and Genetics, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
C M BeauséjourCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine, Montréal, Canada.
Centre Hospitalier Universitaire Sainte-Justine · CAUniversité de Montréal · CAUniversity of North Carolina at Chapel Hill · US

Funding

The Role of p16INK4 in Mammalian AgingR01AG024379 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HE, SHENGHUI · 2004 to 2019
$4.6M
CIHR 102709-1CIHR 102709-2NIA NIH HHS R01 AG024379
6 · The paper itself

Abstract

Exposure of murine and human tissues to ionizing radiation (IR) induces the expression of p16

Indexed as

Radiation, IonizingAnimalsCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p16FemaleMaleMiceMice, KnockoutNeoplasms, ExperimentalCyclin-Dependent Kinase Inhibitor p16

Identifiers

PMID27568978
PMCPMC5336385
OpenAlexW2510862022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.