Evidence map›Paper›PMID 27568901›Full record

Observational studyJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2016

Outcomes Associated with Early Postoperative Noninvasive Ventilation in Bariatric Surgical Patients with Sleep Apnea.

Mihaela S Stefan, Nicholas S Hill, Karthik Raghunathan, Xiaoxia Liu, Penelope S Pekow, Stavros G Memtsoudis, Satya Krishna Ramachandran, Peter K Lindenauer

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Use and limitations of databases and big data in sleep-disordered breathing research.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  2. ISCCM Guidelines for the Use of Non-invasive Ventilation in Acute Respiratory Failure in Adult ICUs.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Mihaela S StefanCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Nicholas S HillDivision of Pulmonary and Critical Care Medicine, Tufts University School of Medicine, Boston, MA.
Karthik RaghunathanAnesthesiology Service, Durham VA Medical Center, Duke University Medical Center, Durham, NC.
Xiaoxia LiuCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Penelope S PekowCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Stavros G MemtsoudisDepartment of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College of Cornell University, New York, NY.
Satya Krishna RamachandranDepartment of Anesthesiology, University of Michigan Health System, Ann Arbor, MI.
Peter K LindenauerCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Baystate Medical Center · USTufts University · USDuke University Hospital · USHospital for Special Surgery · USMichigan Medicine · US

Funding

Research and Mentoring in Comparative Effectiveness and Implementation ScienceK24HL132008 · NHLBI · BAYSTATE MEDICAL CENTER, INC. · PI LINDENAUER, PETER KYLE · 2016 to 2020
$574k
NHLBI NIH HHS K24 HL132008
6 · The paper itself

Abstract

STUDY

objectivesTo examine the relationship of early initiation of noninvasive ventilation (NIV) with postoperative outcomes in patients with obstructive sleep apnea (OSA) undergoing bariatric surgery.

methodsWe included 5,266 patients with OSA undergoing bariatric surgeries at 161 hospitals in the United States. We defined early postoperative NIV as NIV used on the day of or the day after surgery; this could include prophylactic NIV or NIV used for early signs of respiratory deterioration. We developed a hierarchical model to identify factors associated with early use of NIV. Then, in a propensity matched cohort, we assessed the association between NIV use and outcomes.

resultsOverall, 996 patients (18.9%) were treated with early postoperative NIV. Predictors of NIV initiation were: male sex (odds ratio: 1.34, 95% confidence interval 1.14-1.59), older age, chronic obstructive pulmonary disease (COPD; odds ratio 1.39, confidence interval: 1.17-1.64), gastric bypass surgery, short-acting narcotics intravenous on the day of surgery and admission to a hospital with high rate of OSA diagnosis. In a propensity matched analysis, we found no significant association between early initiation of NIV and receipt of invasive mechanical ventilation (IMV) (early NIV 4.5% vs. no NIV 3.8% p = 0.46), cardiovascular complications or mortality. Results were consistent in several sensitivity analyses.

conclusionsIn this large observational study of patients with OSA undergoing bariatric surgery, early postoperative NIV use was not associated with better outcomes including less intubation and mortality. Properly designed controlled trials will be necessary to provide more definitive answers to this important clinical question.

Indexed as

Bariatric SurgeryAdultCohort StudiesFemaleHumansMaleMiddle AgedNoninvasive VentilationPostoperative ComplicationsRetrospective StudiesSleep Apnea, ObstructiveTreatment Outcomecontinuous positive pressure ventilationgeneral surgeryoutcome researchsleep disorders

Identifiers

PMID27568901
PMCPMC5078706
OpenAlexW2509754418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.