Evidence map›Paper›PMID 27568881›Full record

ArticleBMC medicine2016

The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases.

Mome Mukherjee, Andrew Stoddart, Ramyani P Gupta, Bright I Nwaru, Angela Farr, Martin Heaven, Deborah Fitzsimmons, Amrita Bandyopadhyay, Chantelle Aftab, Colin R Simpson and 9 more

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 150 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 13 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03511482 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

An Open Feasibility Study to Investigate the Impact of A Digitally Delivered Asthma Service for Patients in Primary Care (IDEAL-001: Integrated Digitally EnhAnced Care for Long-term Conditions-001

TypeinterventionalSponsormy mhealth LtdRan2019 to 2021Enrolled0ConditionsAsthmaArmsmyAsthma Application, Lloyds Pharmacy Online Doctor
NCT04744272 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

A Randomised Controlled Feasibility Study to Explore the Efficacy of Digital Self-management Within Secondary Care in an Asthmatic Population

TypeinterventionalSponsormy mhealth LtdRan2022 to 2023Enrolled0ConditionsAsthmaArmsmyAsthma
NCT06447974 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Barts Charity Children's Environmental Health Clinic

TypeinterventionalSponsorQueen Mary University of LondonRan2025 to 2027Enrolled200ConditionsEnvironmental Exposure, Health Behavior, Asthma in Children, Environmental IllnessArmsExposure mitigations
3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 13 syntheses or guidelines pooled it, 286 citations in OpenAlex.

  1. Validating exacerbations of asthma in electronic health records: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Anti-IL-5 therapies for asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Statins for asthma.The Cochrane database of systematic reviews · 2020
    Pooled it
  10. Pooled it
  11. Anti-IL5 therapies for asthma.The Cochrane database of systematic reviews · 2017
    Pooled it
  12. Pooled it
  13. Pooled it
  14. Trial
  15. Trial
  16. Article
  17. Article
  18. Describing the burden and characteristics ofBMJ open respiratory research · 2026
    Article
  19. Article
  20. Article

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 3 countries.

Mome MukherjeeAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK. mome.mukherjee@ed.ac.uk.ORCID 0000-0002-3083-436X
Andrew StoddartAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Ramyani P GuptaPopulation Health Research Institute, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK.
Bright I NwaruAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Angela FarrSwansea Centre for Health Economics (SCHE), College of Human and Health Science, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
Martin HeavenFarr Institute, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.
Deborah FitzsimmonsSwansea Centre for Health Economics (SCHE), College of Human and Health Science, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
Amrita BandyopadhyayFarr Institute, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.
Chantelle AftabThe University of Edinburgh & The Royal College of Surgeons of Edinburgh, Clinical Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Colin R SimpsonAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Ronan A LyonsFarr Institute, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.
Colin FischbacherInformation Services Division (ISD), NHS National Services Scotland, Room 111, Gyle Square, 1 South Gyle Crescent, Edinburgh, EH12 9EB, UK.
Christopher DibbenSchool of Geosciences, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Michael D ShieldsCentre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Wellcome Wolfson Institute Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
Ceri J PhillipsSwansea Centre for Health Economics (SCHE), College of Human and Health Science, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
David P StrachanPopulation Health Research Institute, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK.
Gwyneth A DaviesAsthma & Allergy Group, Institute of Life Science, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
Brian McKinstryEdinburgh Clinical Trials Unit, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Aziz SheikhAsthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Swansea University · GBAsthma UK · GBSt George's, University of London · GBUniversity of Edinburgh · GBCentre for Global Health Research · CANational Health Service Scotland · GBQueen's University Belfast · GBRoyal College of Surgeons of Edinburgh · GBTampere University · FI

Funding

Arthritis Research UKBritish Heart FoundationCancer Research UKChief Scientist OfficeMedical Research Council G1000758Medical Research Council MC_PC_13040Medical Research Council MR/K006525/1Medical Research Council MR/K007017/1
6 · The paper itself

Abstract

backgroundThere are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of the epidemiology, healthcare utilisation and costs of asthma.

methodsWe obtained and analysed asthma-relevant data from 27 datasets: these comprised national health surveys for 2010-11, and routine administrative, health and social care datasets for 2011-12; 2011-12 costs were estimated in pounds sterling using economic modelling.

resultsThe prevalence of asthma depended on the definition and data source used. The UK lifetime prevalence of patient-reported symptoms suggestive of asthma was 29.5 % (95 % CI, 27.7-31.3; n = 18.5 million (m) people) and 15.6 % (14.3-16.9, n = 9.8 m) for patient-reported clinician-diagnosed asthma. The annual prevalence of patient-reported clinician-diagnosed-and-treated asthma was 9.6 % (8.9-10.3, n = 6.0 m) and of clinician-reported, diagnosed-and-treated asthma 5.7 % (5.7-5.7; n = 3.6 m). Asthma resulted in at least 6.3 m primary care consultations, 93,000 hospital in-patient episodes, 1800 intensive-care unit episodes and 36,800 disability living allowance claims. The costs of asthma were estimated at least £1.1 billion: 74 % of these costs were for provision of primary care services (60 % prescribing, 14 % consultations), 13 % for disability claims, and 12 % for hospital care. There were 1160 asthma deaths.

conclusionsAsthma is very common and is responsible for considerable morbidity, healthcare utilisation and financial costs to the UK public sector. Greater policy focus on primary care provision is needed to reduce the risk of asthma exacerbations, hospitalisations and deaths, and reduce costs.

Indexed as

Cost of IllnessAsthmaDatabases, FactualHealth Care CostsHealth SurveysHumansPrevalenceUnited KingdomAsthmaBurdenCostEpidemiologyUK

Identifiers

PMID27568881
PMCPMC5002970
OpenAlexW2490831979

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.