ArticleClinical breast cancer2017
Invasive Breast Cancer Preferably and Predominantly Occurs at the Interface Between Fibroglandular and Adipose Tissue.
Article in Clinical breast cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- 3D Bioprinted Breast Cancer-Stroma Model with Tailored Migration-Permissive Bioink Reveals Impact of Adipose-Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics.Advanced healthcare materials · 2026Article
- Estimation of fatty acid composition in mammary adipose tissue using deep neural network with unsupervised training.Magnetic resonance in medicine · 2025Article
- A conditional inference tree model for predicting cancer risk of non-mass lesions detected on breast ultrasound.European radiology · 2024Article
- Breast Tomographic Ultrasound: The Spectrum from Current Dense Breast Cancer Screenings to Future Theranostic Treatments.Tomography (Ann Arbor, Mich.) · 2024Review
- Development and Clinical Validation of a Novel 5 Gene Signature Based on Fatty Acid Metabolism-Related Genes in Oral Squamous Cell Carcinoma.Oxidative medicine and cellular longevity · 2022Article
- The Potential Role of the Fat-Glandular Interface (FGI) in Breast Carcinogenesis: Results from an Ultrasound Tomography (UST) Study.Journal of clinical medicine · 2021Article
- Bilateral gradient-echo spectroscopic imaging with correction of frequency variations for measurement of fatty acid composition in mammary adipose tissue.Magnetic resonance in medicine · 2021Article
- Early detection breast cancer: role of circulating plasma miRNA-21 expression as a potential screening biomarkerTurkish journal of medical sciences · 2021Article
- Body Composition Analysis of 10 Years versus 5 Years of Adjuvant Endocrine Therapy in Patients with Nonmetastatic Breast Cancer.Journal of oncology · 2021Article
- Role of TG2 and TGF-βOncology letters · 2020Article
- Fatty acid composition in mammary adipose tissue measured by Gradient-echo Spectroscopic MRI and its association with breast cancers.European journal of radiology · 2019Article
- Quantitative analysis of peri-tumor fat in different molecular subtypes of breast cancer.Magnetic resonance imaging · 2018Article
- The potential role of leptin in tumor invasion and metastasis.Cytokine & growth factor reviews · 2017Review
- MED23 in endocrinotherapy for breast cancer.Oncology letters · 2017Article
- Impact of Different Analytic Approaches on the Analysis of the Breast Fibroglandular Tissue Using Diffusion Weighted Imaging.BioMed research international · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundIncreasing evidence suggests adipocyte involvement in malignant breast tumor invasive front or margin. The aim of this study was to evaluate the location of invasive breast tumors in relation to fibroglandular and adipose tissue by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). PATIENTS AND
methodsPretreatment breast DCE-MRI images of 294 patients with biopsy-proven invasive breast cancer from 2008 to 2014 were studied. Invasive breast tumors were visualized as enhanced lesions in the postcontrast subtraction images. Positive identification of biopsy-confirmed invasive breast tumors on DCE-MRI images was achieved by correlation of findings from breast MRI and pathology reports. Tumor location in relation to fibroglandular and adipose tissue was investigated using precontrast T1-weighted MRI images.
resultsOf 294 patients, 291 had DCE-MRI discernable invasive breast tumors located at the interface between fibroglandular and adipose tissues, regardless of the tumor size, type, receptor status, or breast composition.
conclusionInvasive breast cancer preferably and predominantly occurs adjacent to breast adipose tissue.
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