Evidence map›Paper›PMID 27568069›Full record

Trial reportContemporary clinical trials2016

Efficacy of smoking cessation therapy alone or integrated with prolonged exposure therapy for smokers with PTSD: Study protocol for a randomized controlled trial.

Mark B Powers, Brooke Y Kauffman, Anne L Kleinsasser, Eunjung Lee-Furman, Jasper A J Smits, Michael J Zvolensky, David Rosenfield

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. E-cigarette use (vaping) is associated with illicit drug use, mental health problems, and impulsivity in university students.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mark B PowersDepartment of Psychology, Institute of Mental Health Research, University of Texas at Austin, Austin, TX, United States. Electronic address: mbpowers@utexas.edu.
Brooke Y KauffmanDepartment of Psychology, University of Houston, Houston, TX, United States.
Anne L KleinsasserDepartment of Psychology, Institute of Mental Health Research, University of Texas at Austin, Austin, TX, United States; Department of Psychology, Baylor University, Waco, TX, United States.
Eunjung Lee-FurmanDepartment of Psychology, Institute of Mental Health Research, University of Texas at Austin, Austin, TX, United States.
Jasper A J SmitsDepartment of Psychology, Institute of Mental Health Research, University of Texas at Austin, Austin, TX, United States.
Michael J ZvolenskyDepartment of Psychology, University of Houston, Houston, TX, United States; Department of Behavioral Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
David RosenfieldDepartment of Psychology, Southern Methodist University, Dallas, TX, United States.
Baylor University · USSouthern Methodist University · USThe University of Texas at Austin · USThe University of Texas MD Anderson Cancer Center · USUniversity of Houston · US

Funding

Integrated PTSD and Smoking TreatmentK01DA035930 · NIDA · UNIVERSITY OF TEXAS AT AUSTIN · PI POWERS, MARK B · 2013 to 2017
$857k
NIDA NIH HHS K01 DA035930
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) is related to an increased risk of smoking cessation failure. In fact, the quit rate in smokers with PTSD (23.2%) is one of the lowest of all mental disorders. Features of PTSD that contribute to smokers' progression to nicotine dependence and cessation relapse include negative affect, fear, increased arousal, irritability, anger, distress intolerance, and anxiety sensitivity. Anxiety sensitivity is higher in people with PTSD than in any other anxiety disorder except for panic disorder. High anxiety sensitivity is uniquely associated with greater odds of lapse and relapse during quit attempts. Distress intolerance, a perceived or behavioral tendency to not tolerate distress, is related to both the maintenance of PTSD and problems in quitting smoking. Prolonged exposure (PE) and interoceptive exposure (IE) reduce PTSD symptoms, distress intolerance, and anxiety sensitivity. Thus, they emerge as promising candidates to augment standard smoking cessation interventions for individuals with PTSD. The present study tests a 12-session specialized treatment for smokers with PTSD. This Integrated PTSD and Smoking Treatment (IPST) combines cognitive-behavioral therapy and nicotine replacement treatment for smoking cessation (standard care; SC) with PE to target PTSD symptoms and IE to reduce anxiety sensitivity and distress intolerance. Adult smokers (N=80) with PTSD will be randomly assigned to either: (1) IPST or (2) SC. Primary outcomes are assessed at weeks 0, 6, 8, 10, 14, 16, 22, and 30.

Indexed as

Research DesignTobacco Use Cessation DevicesAdolescentAdultAgedAnxiety DisordersCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSmoking CessationSocioeconomic FactorsStress Disorders, Post-TraumaticTime FactorsYoung AdultBehavioral interventionClinical trialPTSDSmoking cessation

Identifiers

PMID27568069
PMCPMC5695545
OpenAlexW2513068825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.