SynthesisInternational journal of colorectal disease2017
Laparoscopic lavage is superior to colon resection for perforated purulent diverticulitis-a meta-analysis.
Synthesis in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A National, Registry Based Study of Clinical Results After Emergency Operation for Perforated Diverticulitis to Compare Laparoscopic Lavage and Resection Surgery in Routine Use.
Scandinavian Diverticulitis Trial SCANDIV II: Treatment of Acute Complicated Diverticulitis: a Prospective Observational Study
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting.World journal of emergency surgery : WJES · 2020Guideline
- Laparoscopic lavage and drainage for Hinchey III diverticulitis: review of technical aspects.Updates in surgery · 2019Pooled it
- Perforated sigmoid diverticulitis: Hartmann's procedure or resection with primary anastomosis-a systematic review and meta-analysis of randomised control trials.Techniques in coloproctology · 2018Pooled it
- Laparoscopic lavage versus surgical resection for acute diverticulitis with generalised peritonitis: a systematic review and meta-analysis.Techniques in coloproctology · 2017Pooled it
- Two-year results of the randomized clinical trial DILALA comparing laparoscopic lavage with resection as treatment for perforated diverticulitis.The British journal of surgery · 2018Trial
- Laparoscopic lavage: an option for surgical management of complicated diverticulitis.Surgical endoscopy · 2025Review
- Long-Term Results After Laparoscopic Lavage for Perforated Diverticulitis Purulent Peritonitis in Sweden: A Population-Based Observational Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Diverticulitis, surgery, evidence-based medicine, and the Steve Jobs' dots: a narrative review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Review
- Functional Outcomes of Emergency Surgery for Perforated Diverticulitis, Hinchey Grade III.World journal of surgery · 2023Observational
- Current Aspects on the Management of Perforated Acute Diverticulitis: A Narrative Review.Cureus · 2022Review
- Laparoscopic Lavage in the Management of Hinchey III/IV Diverticulitis.Clinics in colon and rectal surgery · 2021Review
- Management of perforated diverticulitis with generalized peritonitis. A multidisciplinary review and position paper.Techniques in coloproctology · 2021Review
- Laparoscopic peritoneal lavage versus laparoscopic sigmoidectomy in complicated acute diverticulitis: a multicenter prospective observational study.International journal of colorectal disease · 2019Observational
- Perforated diverticulitis in the North of England: trends in patient outcomes, management approach and the influence of subspecialisation.Annals of the Royal College of Surgeons of England · 2019Article
- Long-term follow-up of a multicentre cohort study on laparoscopic peritoneal lavage for perforated diverticulitis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2019Article
- The Multidisciplinary Management of Acute Complicated Diverticulitis.Inflammatory intestinal diseases · 2018Review
- Perforated sigmoid diverticulitis: Hartmann's procedure or resection with primary anastomosis.Techniques in coloproctology · 2018Article
- Secondary peritonitis: principles of diagnosis and intervention.BMJ (Clinical research ed.) · 2018Review
- Inflammation management in acute diverticulitis: current perspectives.Journal of inflammation research · 2018Review
- Management of Diverticulitis in 2017.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePerforated diverticulitis often requires surgery with a colon resection such as Hartmann's procedure, with inherent morbidity. Recent studies suggest that laparoscopic lavage may be an alternative surgical treatment. The aim of this study was to compare re-operations, morbidity, and mortality as well as health economic outcomes between laparoscopic lavage and colon resection for perforated purulent diverticulitis.
methodsPubMed, Cochrane, Centre for Reviews and Dissemination, and Embase were searched. Published randomized controlled trials and prospective and retrospective cohorts with laparoscopic lavage and colon resection as interventions were identified. Trial limitations were assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Re-operations, complications at 90 days classified according to Clavien-Dindo and mortality were extracted.
resultsThree randomized trials published between 2005 and 2015 were included in the analysis. The studies included a total of 358 patients with 185 patients undergoing laparoscopic lavage. At 12 months, the relative risk of having a re-operation was lower for laparoscopic lavage compared to colon resection in the two trials that had a 12 month follow-up. We found no significant differences in Clavien-Dindo complications classified more than level IIIB or mortality at 90 days.
conclusionsThe risk for re-operations within the first 12 months after index surgery was lower for laparoscopic lavage compared to colon resection, with overall comparable morbidity and mortality. Furthermore, Hartmann's resection was more costly than laparoscopic lavage. We therefore consider laparoscopic lavage a valid alternative to surgery with resection for perforated purulent diverticulitis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.