Evidence map›Paper›PMID 27567919›Full record

ArticleMycopathologia2016

Biophysical Effects of a Polymeric Biosurfactant in Candida krusei and Candida albicans Cells.

Gabriella Freitas Ferreira, Bruna Lorrana Dos Santos Pinto, Eliene Batista Souza, José Lima Viana, Adrielle Zagmignan, Julliana Ribeiro Alves Dos Santos, Áquila Rodrigues Costa Santos, Priscila Batista Tavares, Ângelo Márcio Leite Denadai, Andrea Souza Monteiro

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Magnetic Removal ofInternational journal of nanomedicine · 2023
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  9. Evaluation ofFrontiers in microbiology · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Gabriella Freitas FerreiraDepartamento de Farmácia, Universidade Federal de Juiz de Fora - Campus Governador Valadares, Av. Dr. Raimundo Monteiro de Rezende, 330, Centro, Governador Valadares, MG, 35010-177, Brazil. gabriella.freitas@ufjf.edu.br.ORCID http://orcid.org/0000-0001-6842-1934
Bruna Lorrana Dos Santos PintoLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
Eliene Batista SouzaLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
José Lima VianaLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
Adrielle ZagmignanLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
Julliana Ribeiro Alves Dos SantosLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
Áquila Rodrigues Costa SantosUniversidade Vale do Rio Doce, Rua Israel Pinheiro, 2000, Universitário, Governador Valadares, MG, 35020-220, Brazil.
Priscila Batista TavaresUniversidade Vale do Rio Doce, Rua Israel Pinheiro, 2000, Universitário, Governador Valadares, MG, 35020-220, Brazil.
Ângelo Márcio Leite DenadaiDepartamento de Farmácia, Universidade Federal de Juiz de Fora - Campus Governador Valadares, Av. Dr. Raimundo Monteiro de Rezende, 330, Centro, Governador Valadares, MG, 35010-177, Brazil.
Andrea Souza MonteiroLaboratório de Biologia Parasitária, Universidade CEUMA, Rua Josué Montello, 1, Renascença II, São Luís, MA, 65075-120, Brazil.
Universidade Federal de Juiz de Fora · BRUniversidade Vale do Rio Doce · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of a polymeric biosurfactant produced by Trichosporon montevideense CLOA72 in the adhesion of Candida albicans and Candida krusei cells to human buccal epithelial cells and its interference in biofilm formation by these strains. The biofilm inhibition by biosurfactant (25 mg/mL) in C. krusei and C. albicans in polystyrene was reduced up to 79.5 and 85 %, respectively. In addition, the zeta potential and hydrodynamic diameter of the yeasts altered as a function of the biosurfactant concentration added to the cell suspension. The changes in the cell surface characteristics and the interface modification can contribute to the inhibition of the initial adherence of yeasts cells to the surface. In addition, the analyses of the biofilm matrix and planktonic cell surfaces demonstrated differences in carbohydrate and protein concentrations for the two studied strains, which may contribute to the modulation of cell adhesion or consolidation of biofilms, especially in C. krusei. This study suggests a possible application of the of CLOA72 biosurfactant in inhibiting the adhesion and formation of biofilms on biological surfaces by yeasts of the Candida genus.

Indexed as

Antifungal AgentsBiofilmsBiophysical PhenomenaBiopolymersCandidaCell AdhesionCells, CulturedEpithelial CellsHealthy VolunteersHumansSurface-Active AgentsTrichosporonAntifungal AgentsBiopolymersSurface-Active AgentsBiofilmBiosurfactantCandida albicansCandida krusei

Identifiers

PMID27567919
OpenAlexW2516730908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.