Evidence map›Paper›PMID 27567601›Full record

ArticleNeurobiology of disease2016

Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease.

Xavier Guitart, Jordi Bonaventura, William Rea, Marco Orrú, Lucrezia Cellai, Ilaria Dettori, Felicita Pedata, Marc Brugarolas, Antonio Cortés, Vicent Casadó and 4 more

Open access · greenAbstract read
In one paragraph

Article in Neurobiology of disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Indirect Medium Spiny Neurons in the Dorsomedial Striatum Regulate Ethanol-Containing Conditioned Reward Seeking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease.Journal of caffeine and adenosine research · 2018
    Review
  12. Differential gene regulatory networks in development and disease.Cellular and molecular life sciences : CMLS · 2018
    Review
  13. Emerging Roles of Nucleoside Transporters.Frontiers in pharmacology · 2018
    Article
  14. Article
  15. The Role of Adenosine ABioMed research international · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Xavier GuitartIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States.
Jordi BonaventuraIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States.
William ReaIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States.
Marco OrrúIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States.
Lucrezia CellaiDepartment NEUROFARBA, Division of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Ilaria DettoriDepartment NEUROFARBA, Division of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Felicita PedataDepartment NEUROFARBA, Division of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Marc BrugarolasDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona and Center for Biomedical Research in Neurodegenerative Diseases Network and Institute of Biomedicine, 08028 Barcelona, Spain.
Antonio CortésDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona and Center for Biomedical Research in Neurodegenerative Diseases Network and Institute of Biomedicine, 08028 Barcelona, Spain.
Vicent CasadóDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona and Center for Biomedical Research in Neurodegenerative Diseases Network and Institute of Biomedicine, 08028 Barcelona, Spain.
Ching-Pang ChangDivision of Neuroscience Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.
Manikandan NarayananSystems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, United States.
Yijuang ChernDivision of Neuroscience Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.
Sergi FerréIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States. Electronic address: sferre@intra.nida.nih.gov.
National Institutes of Health · USBiomedical Research Networking Center on Neurodegenerative Diseases · ESUniversity of Florence · ITInstitute of Biomedical Sciences, Academia Sinica · TW

Funding

Neurotransmitter Receptor Heteromers in the Striatal Spine ModuleZIADA000493 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI FERRE, SERGI · 2009 to 2025
$35.6M
Neurotransmitter Receptor Heteromers in the Striatal Spine ModuleZ01DA000493 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI GOLDBERG, STEVEN R · 2006 to 2008
$691k
Intramural NIH HHS Z01 DA000493
6 · The paper itself

Abstract

The initial goal of this study was to investigate alterations in adenosine A

Indexed as

AdenosineAdenosine A2 Receptor AntagonistsAnimalsBiomarkersCorpus StriatumDisease Models, AnimalGene Expression RegulationHumansHuntingtin ProteinHuntington DiseaseLocomotionNucleoside Transport ProteinsPrefrontal CortexPsychomotor DisordersPurinesRatsAdenosineAdenosine A2 Receptor AntagonistsBiomarkersHtt protein, ratHuntingtin ProteinistradefyllineNucleoside Transport ProteinsPurinesReceptor, Adenosine A2ATriazinesTriazolesTritiumZM 241385A(2A) receptorAdenosineENT1Huntington disease

Identifiers

PMID27567601
PMCPMC5102769
OpenAlexW2510857012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.