ArticleJournal of experimental botany2016
The GhTT2_A07 gene is linked to the brown colour and natural flame retardancy phenotypes of Lc1 cotton (Gossypium hirsutum L.) fibres.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Genome-wide integrative dissection of genetic basis of fiber color and whiteness regulation in upland cotton (Gossypium hirsutum).BMC biology · 2026Article
- Graph pan-genome illuminates evolutionary trajectories and agronomic trait architecture in allotetraploid cotton.Nature genetics · 2026Article
- Genetic basis and role of exotic accessions in cultivated cotton fiber quality improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Allele and transcriptome mining in Gossypium hirsutum reveals variation in candidate genes at genetic loci affecting cotton fiber quality and textile flammability.BMC plant biology · 2025Article
- Article
- The brown fiber phenotype in cotton line SA-40 is linked to a missing Ty3-like retrotransposon upstream of theFrontiers in plant science · 2025Article
- TRANSPARENT TESTA 16 collaborates with the MYB-bHLH-WD40 transcriptional complex to produce brown fiber cotton.Plant physiology · 2024Article
- Integrative Transcriptomic and Metabolic Analyses Reveal That Flavonoid Biosynthesis Is the Key Pathway Regulating Pigment Deposition in Naturally Brown Cotton Fibers.Plants (Basel, Switzerland) · 2024Article
- Naturally colored cotton for wearable applications.Frontiers in plant science · 2024Review
- Multi-omics analysis of pigmentation related to proanthocyanidin biosynthesis in brown cotton (Frontiers in plant science · 2024Article
- A glutathione S-transferase GhTT19 determines flower petal pigmentation via regulating anthocyanin accumulation in cotton.Plant biotechnology journal · 2023Article
- Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population.PloS one · 2023Article
- Function deficiency of GhOMT1 causes anthocyanidins over-accumulation and diversifies fibre colours in cotton (Gossypium hirsutum).Plant biotechnology journal · 2022Article
- Article
- Biochemical and Expression Analyses Revealed the Involvement of Proanthocyanidins and/or Their Derivatives in Fiber Pigmentation ofInternational journal of molecular sciences · 2022Article
- Transcriptome Co-expression Network and Metabolome Analysis Identifies Key Genes and Regulators of Proanthocyanidins Biosynthesis in Brown Cotton.Frontiers in plant science · 2021Article
- Functional analysis of GhCHS, GhANR and GhLAR in colored fiber formation of Gossypium hirsutum L.BMC plant biology · 2019Article
- Updates on molecular mechanisms in the development of branched trichome in Arabidopsis and nonbranched in cotton.Plant biotechnology journal · 2019Review
- The WRKY transcription factor GhWRKY27 coordinates the senescence regulatory pathway in upland cotton (Gossypium hirsutum L.).BMC plant biology · 2019Article
- Up-regulation of GhTT2-3A in cotton fibres during secondary wall thickening results in brown fibres with improved quality.Plant biotechnology journal · 2018Article
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10 authors.
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Abstract
Some naturally coloured brown cotton fibres from accessions of Gossypium hirsutum L. can be used to make textiles with enhanced flame retardancy (FR). Several independent brown fibre loci have been identified and mapped to chromosomes, but the underlying genes have not yet been identified, and the mechanism of lint fibre FR is not yet fully understood. In this study, we show that both the brown colour and enhanced FR of the Lc1 lint colour locus are linked to a 1.4Mb inversion on chromosome A07 that is immediately upstream of a gene with similarity to Arabidopsis TRANSPARENT TESTA 2 (TT2). As a result of the alternative upstream sequence, the transcription factor GhTT2_A07 is highly up-regulated in developing fibres. In turn, genes in the phenylpropanoid metabolic pathway are activated, leading to biosynthesis of proanthocyanidins and accumulation of inorganic elements. We show that enhanced FR and anthocyanin precursors appear in developing brown fibres well before the brown colour is detectible, demonstrating for the first time that the polymerized proanthocyanidins that constitute the brown colour are not the source of enhanced FR. Identifying the particular colourless metabolite that provides Lc1 cotton with enhanced FR could help minimize the use of synthetic chemical flame retardant additives in textiles.
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