ArticleOccupational and environmental medicine2017
Development of a job-task-exposure matrix to assess occupational exposure to disinfectants among US nurses.
Article in Occupational and environmental medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Bus-exposure matrix, a tool to assess bus drivers' exposure to physicochemical hazards.Annals of work exposures and health · 2025Article
- Occupational Exposure Patterns to Disinfectants and Cleaning Products and Its Association With Asthma Among French Healthcare Workers.American journal of industrial medicine · 2025Article
- Occupational Exposure to Disinfectants and Risk of Incident Cardiovascular Disease among US Nurses: The Nurses' Health Study II.Environmental health perspectives · 2025Article
- Work-Related Stress, Professional Respect, and Psychological Counseling Among Nurses: A Cross-Sectional Study.Journal of nursing management · 2025Article
- Development and validation of a French job-exposure matrix for healthcare workers: JEM Soignances.Scandinavian journal of work, environment & health · 2024Article
- Knowledge, attitude, and practice toward the prevention of occupational exposure in public health emergencies among nurses in Wuhan.Frontiers in public health · 2024Article
- Exposure frequency, intensity, and duration: What we know about work-related asthma risks for healthcare workers from cleaning and disinfection.Journal of occupational and environmental hygiene · 2023Review
- A qualitative characterization of meso-activity factors to estimate soil exposure for agricultural workers.Journal of exposure science & environmental epidemiology · 2023Article
- Characterization of Exposure to Cleaning Agents Among Health Workers in Two Southern African Tertiary Hospitals.Annals of work exposures and health · 2022Article
- Occupational Exposures to Organic Solvents and Asthma Symptoms in the CONSTANCES Cohort.International journal of environmental research and public health · 2021Article
- Occupational exposure to disinfectants and asthma incidence in U.S. nurses: A prospective cohort study.American journal of industrial medicine · 2020Article
- Peak Inhalation Exposure Metrics Used in Occupational Epidemiologic and Exposure Studies.Frontiers in public health · 2020Review
- Association of Occupational Exposure to Disinfectants With Incidence of Chronic Obstructive Pulmonary Disease Among US Female Nurses.JAMA network open · 2019Article
- Using Decision Rules to Assess Occupational Exposure in Population-Based Studies.Current environmental health reports · 2019Review
- Peaks, Means, and Determinants of Real-Time TVOC Exposures Associated with Cleaning and Disinfecting Tasks in Healthcare Settings.Annals of work exposures and health · 2019Article
- Methodological evaluation of human research on asthmagenicity and occupational cleaning: a case study of quaternary ammonium compounds ("quats").Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Review
- Exposures to Volatile Organic Compounds among Healthcare Workers: Modeling the Effects of Cleaning Tasks and Product Use.Annals of work exposures and health · 2018Article
- Association of hand and arm disinfection with asthma control in US nurses.Occupational and environmental medicine · 2018Article
- Occupational exposure to disinfectants and asthma control in US nurses.The European respiratory journal · 2017Article
- An Official American Thoracic Society Workshop Report: Presentations and Discussion of the Sixth Jack Pepys Workshop on Asthma in the Workplace.Annals of the American Thoracic Society · 2017Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
Abstract
objectivesOccupational exposure to disinfectants is associated with work-related asthma, especially in healthcare workers. However, little is known about the specific products involved. To evaluate disinfectant exposures, we designed job-exposure (JEM) and job-task-exposure (JTEM) matrices, which are thought to be less prone to differential misclassification bias than self-reported exposure. We then compared the three assessment methods: self-reported exposure, JEM and JTEM.
methodsDisinfectant use was assessed by an occupational questionnaire in 9073 US female registered nurses without asthma, aged 49-68 years, drawn from the Nurses' Health Study II. A JEM was created based on self-reported frequency of use (1-3, 4-7 days/week) of 7 disinfectants and sprays in 8 nursing jobs. We then created a JTEM combining jobs and disinfection tasks to further reduce misclassification. Exposure was evaluated in 3 classes (low, medium, high) using product-specific cut-offs (eg, <30%, 30-49.9%, ≥50%, respectively, for alcohol); the cut-offs were defined from the distribution of self-reported exposure per job/task.
resultsThe most frequently reported disinfectants were alcohol (weekly use: 39%), bleach (22%) and sprays (20%). More nurses were classified as highly exposed by JTEM (alcohol 41%, sprays 41%, bleach 34%) than by JEM (21%, 30%, 26%, respectively). Agreement between JEM and JTEM was fair-to-moderate (κ 0.3-0.5) for most disinfectants. JEM and JTEM exposure estimates were heterogeneous in most nursing jobs, except in emergency room and education/administration.
conclusionsThe JTEM may provide more accurate estimates than the JEM, especially for nursing jobs with heterogeneous tasks. Use of the JTEM is likely to reduce exposure misclassification.
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