ArticleJournal of cancer research and clinical oncology2016
The Glasgow Prognostic Score (GPS) is a novel prognostic indicator in advanced epithelial ovarian cancer: a multicenter retrospective study.
Article in Journal of cancer research and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Impact of residual disease as a prognostic factor for survival in women with advanced epithelial ovarian cancer after primary surgery.The Cochrane database of systematic reviews · 2022Pooled it
- A high Glasgow prognostic score (GPS) or modified Glasgow prognostic score (mGPS) predicts poor prognosis in gynecologic cancers: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2020Pooled it
- Prognostic role of the Glasgow prognostic score and modified Glasgow prognostic score in patients with renal cell carcinoma undergoing immunotherapy: a meta-analysis.Clinics (Sao Paulo, Brazil) · 2026Article
- A novel prognostic score of recurrence for endometrial cancer patients with staging surgery.BMC women's health · 2024Article
- The Influence of Inflammatory and Nutritional Status on the Long-Term Outcomes in Advanced Stage Ovarian Cancer.Cancers · 2024Article
- Article
- Progress in Applicability of Scoring Systems Based on Nutritional and Inflammatory Parameters for Ovarian Cancer.Frontiers in nutrition · 2022Review
- Significance of intra/post-operative prognostic scoring system in hepatectomy for colorectal liver metastases.Annals of gastroenterological surgery · 2022Article
- Prognostic Value of the Lymphocyte-to-Monocyte Ratio in Patients with Parotid Gland Carcinoma.The Laryngoscope · 2021Article
- Links between Inflammation and Postoperative Cancer Recurrence.Journal of clinical medicine · 2021Review
- Prognostic Value of the Glasgow Prognostic Score on Overall Survival in patients with Advanced Non-Small Cell Lung Cancer.Journal of Cancer · 2021Article
- Comparison of inflammation-based prognostic scores as predictors of survival outcomes in patients with germ cell tumors.Investigative and clinical urology · 2021Article
- Baseline nutritional status could be a predictor for radiation esophagitis in esophageal cancer patients undergoing radiotherapy.Annals of translational medicine · 2020Article
- Prognostic Value of Inflammation Biomarkers for Survival of Patients with Neuroblastoma.Cancer management and research · 2020Article
- Pre-treatment Glasgow prognostic score and modified Glasgow prognostic score may be potential prognostic biomarkers in urological cancers: a systematic review and meta-analysis.Annals of translational medicine · 2019Article
- The association between the inflammatory potential of diet and risk of developing, and survival following, a diagnosis of ovarian cancer.European journal of nutrition · 2019Article
- High preoperative Glasgow prognostic score is a negative prognostic factor for patients with endometrial carcinoma.Molecular and clinical oncology · 2018Article
- Significant prognostic difference between Grade Group 4 and 5 in the 2014 International Society of Urological Pathology Grading System for High Grade Prostate Cancer with Bone Metastasis.Prostate international · 2017Article
- Preoperative prognostic nutritional index is a powerful predictor of prognosis in patients with stage III ovarian cancer.Scientific reports · 2017Article
- Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors.Oncotarget · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Glasgow Prognostic Score (GPS), an inflammation-based prognostic score systems composed of C-reactive protein and albumin, has been reported to be predictive of survival in several types of malignancies. The prognostic significance of GPS in epithelial ovarian cancer (EOC) remains unclear. We conducted this study to assess the prognostic value of GPS in a cohort of patients with advanced EOC receiving neoadjuvant chemotherapy (NAC) followed by debulking surgery.
methodsSix hundred and seventy-two patients newly diagnosed with advanced EOC were retrospectively analyzed.
resultsHigh GPS was significantly related to Eastern Cooperative Group performance status, histological type, histological grade and the size of residual tumor after the debulking surgery. In addition, patients with higher GPS at diagnosis achieved lower complete remission rates after NAC (P < 0.05) and had shorter progression-free survival (PFS; P < 0.001) and overall survival (OS; P < 0.001). Multivariate analysis showed high GPS was independent adverse predictors of PFS and OS.
conclusionsOur data demonstrated that GPS at diagnosis is a powerful independent prognostic factor for advanced epithelial ovarian cancer. However, further studies are needed to prospectively validate this prognostic model and investigate the mechanisms underlying the correlation between high GPS and poor prognosis in advanced epithelial ovarian cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.