Evidence map›Paper›PMID 27566674›Full record

ArticleLipids in health and disease2016

The role of active brown adipose tissue (aBAT) in lipid metabolism in healthy Chinese adults.

Xiaoliang Shao, Wei Yang, Xiaonan Shao, Chun Qiu, Xiaosong Wang, Yuetao Wang

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Serum Triglycerides Are Related to Chronic Kidney Disease (CKD) Stage 2 in Young and Middle-Aged Chinese Individuals During Routine Health Examination.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  3. Brown Adipose Tissue Energy Metabolism in Humans.Frontiers in endocrinology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoliang ShaoDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Wei YangDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Xiaonan ShaoDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Chun QiuDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Xiaosong WangDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Yuetao WangDepartment of Nuclear Medicine, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China. yuetao-w@163.com.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of dyslipidemia in China was increased over the last several years. Studies have shown that the activity of aBAT is related to the lipid metabolism. In this study, we analyzed blood lipid level in tumor-free healthy Chinese adults in order to determine the role of aBAT in lipid metabolism.

methodsWe retrospectively analyzed the factors that affect the blood lipid level in 717 tumor-free healthy adults who received blood lipid measurement and PET/CT scan by multivariate regression analysis. We also determined the role of aBAT on lipid profile by case-control study.

results(1) Our results showed that 411 (57.3 %) subjects had dyslipidemia. The prevalence of the subjects with hypercholesteremia, hypertriglyceridemia, low high-density lipoprotein cholesterol and high low-density lipoprotein cholesterol was 9.5 %, 44.4 %, 30.8 % and 1.4 %, respectively. Multivariate logistic regression analysis with dyslipidemia as the dependent variable showed that body mass index (BMI) and smoking are independent risk factors for dyslipidemia (OR > 1, P < 0.05), while the presence of aBAT is the independent protective factor for dyslipidemia (OR < 1, P < 0.05). (2) The incidence of aBAT was 1.81 %. Subjects with aBAT had significantly lower serum triglyceride and higher serum high-density lipoprotein cholesterol than the subjects without aBAT. The serum total cholesterol and low-density lipoprotein cholesterol were not significantly different between the subjects with aBAT and those without aBAT.

conclusionsDyslipidemia is caused by multiple factors and the presence of aBAT is a protective factor for dyslipidemia in healthy Chinese adults.

Indexed as

Lipid MetabolismAdipose Tissue, BrownAdultAsian PeopleDyslipidemiasFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk Factors18F-FluorodeoxyglucoseaBATChineseDyslipidemiaPositron emission tomography

Identifiers

PMID27566674
PMCPMC5000508
OpenAlexW2512697533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.