ArticleBMJ open2016
Lymphadenectomy and health-related quality of life after oesophageal cancer surgery: a nationwide, population-based cohort study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Experiences and requirements in nutritional management of patients with esophageal cancer: a systematic review and qualitative meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Quality of life and survival of achieving textbook outcome for resectable esophageal squamous cell carcinoma.Journal of thoracic disease · 2025Article
- Nutritional literacy of patients who underwent surgery for esophageal cancer based on Nutbeam's health literacy model: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Nationwide survey of the follow-up practices for patients with esophageal carcinoma after radical treatment: historical changes and future perspectives in Japan.Esophagus : official journal of the Japan Esophageal Society · 2022Article
- The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer.Cancer medicine · 2021Article
- Comparisons between minimally invasive and open esophagectomy for esophageal cancer with cervical anastomosis: a retrospective study.Journal of cardiothoracic surgery · 2020Article
- Oesophageal cancer.Nature reviews. Disease primers · 2017Review
- Principles of esophageal cancer surgery, including surgical approaches and optimal node dissection (2-Annals of cardiothoracic surgery · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to clarify whether more extensive surgical lymph node resection during oesophageal cancer surgery influences patients' health-related quality of life (HRQOL).
settingThis was a nationwide Swedish population-based study.
participantsA total of 616 patients who underwent curatively intended oesophageal cancer surgery in 2001-2005 were followed up at 6 months and 5 years after surgery. OUTCOME MEASURES: HRQOL was assessed with the validated European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC QLQ-C30) and the oesophageal cancer-specific module (EORTC QLQ-OES18). The number of removed lymph nodes in relation to HRQOL was analysed using multivariable linear regression, providing mean score differences in HRQOL scores with 95% CIs. The results were adjusted for age, comorbidity, body mass index, tumour stage, tumour histology, postoperative complications and surgeon volume.
resultsThe study included 382 and 136 patients who completed the EORTC questionnaires at 6 months and 5 years following surgery, respectively. In general, HRQOL remained stable over time, with only improvements in role function and appetite loss. A larger number of removed lymph nodes did not decrease the HRQOL measure at 6 months or 5 years after surgery.
conclusionsMore extensive lymphadenectomy during oesophageal cancer surgery might not decrease patients' short-term or long-term HRQOL, but larger studies are needed to establish this potential lack of association.
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