ArticleBrain structure & function2017
Functional and neurochemical interactions within the amygdala-medial prefrontal cortex circuit and their relevance to emotional processing.
Article in Brain structure & function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 49 citations in OpenAlex.
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- Hypothesis on PTSD Pathophysiology: Role of CRH, Noradrenaline, and Glucocorticoid Receptors in an Amygdala-Centered Closed-Loop System.International journal of molecular sciences · 2026Article
- Difficult-to-Treat Anxiety: A Neurocomputational Framework.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Review
- The relationship between gastrointestinal symptoms in FGID patients and D-type personality and emotion regulation strategies.iScience · 2024Article
- Age-related reductions in arousal-enhanced memory are moderated by trait emotion regulation.Scientific reports · 2023Article
- Cross-sectional study of retrospective self-reported childhood emotional neglect and inhibitory neurometabolite levels in the pregenual anterior cingulate cortex in adult humans.Neurobiology of stress · 2023Article
- Optimizing Individual Targeting of Fronto-Amygdala Network with Transcranial Magnetic Stimulation (TMS): Biophysical, Physiological and Behavioral Variations in People with Methamphetamine Use Disorder.medRxiv : the preprint server for health sciences · 2023Article
- Observing cognitive processes in time through functional MRI model comparison.Human brain mapping · 2023Article
- Electrophysiology as a Tool to Decipher the Network Mechanism of Visceral Pain in Functional Gastrointestinal Disorders.Diagnostics (Basel, Switzerland) · 2023Review
- Effective connectivity between deep brain stimulation targets in individuals with treatment-resistant depression.Brain communications · 2023Article
- Altered Medial Prefrontal Connectivity in Parkinson's Disease Patients with Somatic Symptoms.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Morphological similarity of amygdala-ventral prefrontal pathways represents trait anxiety in younger and older adults.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Maturation of Corticolimbic Functional Connectivity During Sensitive Periods of Brain Development.Current topics in behavioral neurosciences · 2022Article
- Neurophysiological Effects of the Anterior Cingulate Cortex on the Exacerbation of Crohn's Disease: A Combined fMRI-MRS Study.Frontiers in neuroscience · 2022Article
- The Development of Externalizing and Internalizing Behaviors Among Youth With or Without a Family History of Substance Use Disorder: The Indirect Effects of Early-Life Stress and Impulsivity.Child psychiatry and human development · 2021Article
- Functions of the ventromedial prefrontal cortex in emotion regulation under stress.Scientific reports · 2021Article
- High γ-Aminobutyric Acid Content Within the Medial Prefrontal Cortex Is a Functional Signature of Somatic Symptoms Disorder in Patients With Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2020Article
- Modulatory effects of dynamic fMRI-based neurofeedback on emotion regulation networks in adolescent females.NeuroImage · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 5 countries.
Funding
Abstract
The amygdala-medial prefrontal cortex (mPFC) circuit plays a key role in emotional processing. GABA-ergic inhibition within the mPFC has been suggested to play a role in the shaping of amygdala activity. However, the functional and neurochemical interactions within the amygdala-mPFC circuits and their relevance to emotional processing remain unclear. To investigate this circuit, we obtained resting-state functional magnetic resonance imaging (rs-fMRI) and proton MR spectroscopy in 21 healthy subjects to assess the potential relationship between GABA levels within mPFC and the amygdala-mPFC functional connectivity. Trait anxiety was assessed using the State-Trait Anxiety Inventory (STAI-Y2). Partial correlations were used to measure the relationships among the functional connectivity outcomes, mPFC GABA levels and STAI-Y2 scores. Age, educational level and amount of the gray and white matters within
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.