ReviewCurrent cardiology reports2016
Rheumatic Heart Disease in the Twenty-First Century.
Review in Current cardiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Cardiac and Obstetric Complications of Pregnant Women with Rheumatic Heart Disease in Sub-Saharan Africa: A Systematic Review.Global heart · 2026Pooled it
- Prevalence of rheumatic heart disease among school children in East Africa: a systematic review and meta-analysis.The Pan African medical journal · 2021Pooled it
- Antimicrobial resistance in Africa: a systematic review.BMC infectious diseases · 2017Pooled it
- An Integrative Review of the Cardiovascular Disease Spectrum: Integrating Multi-Omics and Artificial Intelligence for Precision Cardiology.Diseases (Basel, Switzerland) · 2026Review
- Polymeric mitral valve replacement in rheumatic heart disease: hemodynamic and early clinical outcomes from a dedicated sub-analysis of the India Surgical Trial.Frontiers in cardiovascular medicine · 2026Article
- Addressing the challenge of rheumatic heart disease in Pakistan: A call to action.Dialogues in health · 2025Article
- Changes in the burden and underlying causes of rheumatic heart disease in children and youths, 1990-2021: an analysis of the Global Burden of Disease Study 2021.Frontiers in cardiovascular medicine · 2025Article
- BASELINE CLINICAL CHARACTERISTICS OF CONTEMPORARY ADULT CHRONIC RHEUMATIC HEART DISEASE IN IBADAN, NIGERIA.Annals of Ibadan postgraduate medicine · 2024Article
- Review
- Temporal Trends and Burden of Rheumatic Heart Disease in South Asia: A Comprehensive Analysis of Three Decades from Global Burden of Disease Study.Global heart · 2024Article
- Rheumatic heart disease burden, trends, and inequalities in Asia, 1990-2019.Global health action · 2023Article
- Article
- A new surgical technique for left atrial reduction in giant left atrium.JTCVS techniques · 2023Article
- Analyzing the Complicated Connection Between Intestinal Microbiota and Cardiovascular Diseases.Cureus · 2022Review
- Acute Rheumatic Fever and Rheumatic Heart Disease: Highlighting the Role of Group A Streptococcus in the Global Burden of Cardiovascular Disease.Pathogens (Basel, Switzerland) · 2022Review
- Histopathological Characterization of Mitral Valvular Lesions from Patients with Rheumatic Heart Disease.Arquivos brasileiros de cardiologia · 2021Article
- Microbiota in Gut, Oral Cavity, and Mitral Valves Are Associated With Rheumatic Heart Disease.Frontiers in cellular and infection microbiology · 2021Article
- Treating Children With Advanced Rheumatic Heart Disease in Sub-Saharan Africa: The NGO EMERGENCY's Project at theFrontiers in pediatrics · 2021Article
- Article
- Point-of-care ultrasound: Closing guideline gaps in screening for valvular heart disease.Clinical cardiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Rheumatic heart disease (RHD) is a chronic valvular disease resulting after severe or repetitive episodes of acute rheumatic fever (ARF), an autoimmune response to group A Streptococcus infection. RHD has been almost eliminated with improved social and health infrastructure in affluent countries while it remains a neglected disease with major cause of morbidity and mortality in many low- and middle-income countries, and resource-limited regions of high-income countries. Despite our evolving understanding of the pathogenesis of RHD, there have not been any significant advances to prevent or halt progression of disease in recent history. Long-term penicillin-based treatment and surgery remain the backbone of a RHD control program in the absence of an effective vaccine. The advent of echocardiographic screening algorithms has improved the accuracy of diagnosing RHD and has shed light on the enormous burden of disease. Encouragingly, this has led to a rekindled commitment from researchers in the most affected countries to advocate and take bold actions to end this disease of social inequality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.