ArticleNeuroImage2016
Functional neuroanatomy of arithmetic and word reading and its relationship to age.
Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Neurodevelopmental commonalities in cognitive control networks for mathematics and reading in meta-analysis of 3308 participants.Nature communications · 2025Pooled it
- The neuroscience basis and educational interventions of mathematical cognitive impairment and anxiety: a systematic literature review.Frontiers in psychology · 2023Pooled it
- Experience-dependent cortical plasticity in response to formal schooling: Effects on networks for reading and mathematics.Developmental cognitive neuroscience · 2026Article
- Crossroads in the Learning Brain: The Neural Overlap Between Arithmetic and Phonological Processing.Human brain mapping · 2026Article
- Neuroanatomical, transcriptomic, and molecular correlates of math ability and their prognostic value for predicting learning outcomes.Science advances · 2024Article
- Neurocognitive mechanisms of co-occurring math difficulties in dyslexia: Differences in executive function and visuospatial processing.Developmental science · 2024Article
- Activation and functional connectivity of cerebellum during reading and during arithmetic in children with combined reading and math disabilities.Frontiers in neuroscience · 2024Article
- Arithmetic skills are associated with left fronto-temporal gray matter volume in 536 children and adolescents.NPJ science of learning · 2023Article
- A comparison of functional activation and connectivity of the cerebellum in adults and children during single word processing.Brain and language · 2023Article
- Neurocognitive mechanisms underlying multiplication and subtraction performance in adults and skill development in children: A scoping review.Current opinion in behavioral sciences · 2022Article
- Investigating the association between variability in sulcal pattern and academic achievement.Scientific reports · 2022Article
- Brain Responses to Peer Feedback in Social Media Are Modulated by Valence in Late Adolescence.Frontiers in behavioral neuroscience · 2022Article
- Principal Component Analysis of Oxford Cognitive Screen in Patients With Stroke.Frontiers in neurology · 2022Article
- The Role of Brain Activity in Characterizing Successful Reading Intervention in Children With Dyslexia.Frontiers in neuroscience · 2022Article
- Functional neuroanatomy of arithmetic in monolingual and bilingual adults and children.Human brain mapping · 2021Article
- Decoding the role of the cerebellum in the early stages of reading acquisition.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Neural Correlates of Long-Term Memory Enhancement Following Retrieval Practice.Frontiers in human neuroscience · 2021Article
- The relationship between brain structure and proficiency in reading and mathematics in children, adolescents, and emerging adults.Developmental cognitive neuroscience · 2020Article
- An fMRI study of English and Spanish word reading in bilingual adults.Brain and language · 2020Article
- Early Engagement of Parietal Cortex for Subtraction Solving Predicts Longitudinal Gains in Behavioral Fluency in Children.Frontiers in human neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Arithmetic and written language are uniquely human skills acquired during early schooling and used daily. While prior studies have independently characterized the neural bases for arithmetic and reading, here we examine both skills in a single study to capture their shared and unique cognitive mechanisms, as well as the role of age/experience in modulating their neural representations. We used functional MRI in 7- to 29-year-olds who performed single-digit subtraction, single-digit addition, and single-word reading. Using a factorial design, we examined the main effects of Task (subtraction, addition, reading) and Age (as a continuous variable), and their interactions. A main effect of Task revealed preferential activation for subtraction in bilateral intraparietal sulci and supramarginal gyri, right insula, inferior frontal gyrus, and cingulate. The right middle temporal gyrus and left superior temporal gyrus were preferentially active for both addition and reading, and left fusiform gyrus was preferentially active for reading. A main effect of Age revealed increased activity in older participants in right angular gyrus, superior temporal sulcus, and putamen, and less activity in left supplementary motor area, suggesting a left frontal to right temporo-parietal shift of activity with increasing age/experience across all tasks. Interactions for Task by Age were found in right hippocampus and left middle frontal gyrus, with older age invoking greater activity for addition and at the same time less activity for subtraction and reading. Together, in a study conducted in the same participants using similar task and acquisition parameters, the results reveal the neural substrates of these educationally relevant cognitive skills in typical participants in the context of age/experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.